Protein : Qrob_P0336260.2 Q. robur

Protein Identifier  ? Qrob_P0336260.2 Organism . Name  Quercus robur
Score  72.2 Score Type  egn
Protein Description  (M=3) 2.1.1.226 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase. Code Enzyme  EC:2.1.1.227, EC:2.1.1.226
Gene Prediction Quality  validated Protein length 

Sequence

Length: 269  
Kegg Orthology  K06442

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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0003723 RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
GO:0008168 methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0032259 methylation The process in which a methyl group is covalently attached to a molecule.

20 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_1628240 2 215 + 214 Gaps:2 69.23 312 83.33 6e-124 Hemolysin A putative
blastp_kegg lcl|tcc:TCM_002613 8 215 + 208 Gaps:2 72.41 290 86.19 3e-123 Bacterial hemolysin-related isoform 1
blastp_kegg lcl|vvi:100254915 6 215 + 210 Gaps:2 70.67 300 83.49 3e-122 uncharacterized LOC100254915
blastp_kegg lcl|pop:POPTR_0014s17390g 13 215 + 203 Gaps:4 86.97 238 86.96 1e-121 POPTRDRAFT_573182 hypothetical protein
blastp_kegg lcl|pvu:PHAVU_010G036400g 3 215 + 213 Gaps:2 68.69 313 80.93 2e-118 hypothetical protein
blastp_kegg lcl|cit:102609926 1 215 + 215 Gaps:5 69.62 316 80.45 7e-117 uncharacterized LOC102609926
blastp_kegg lcl|pxb:103934372 5 215 + 211 Gaps:5 63.83 329 82.86 5e-116 uncharacterized LOC103934372
blastp_kegg lcl|pxb:103934359 5 215 + 211 Gaps:5 63.83 329 82.86 5e-116 uncharacterized LOC103934359
blastp_kegg lcl|cam:101498329 4 215 + 212 Gaps:4 69.68 310 79.17 2e-115 putative rRNA methyltransferase YqxC-like
blastp_kegg lcl|mdm:103445327 2 215 + 214 Gaps:5 64.74 329 80.75 2e-115 uncharacterized LOC103445327
blastp_pdb 3opn_A 80 215 + 136 Gaps:5 60.78 232 43.26 2e-29 mol:protein length:232 putative hemolysin
blastp_pdb 3hp7_A 62 215 + 154 Gaps:11 54.64 291 38.99 9e-28 mol:protein length:291 Hemolysin putative
blastp_uniprot_sprot sp|Q50760|TLYA_MYCTU 31 215 + 185 Gaps:5 70.90 268 42.11 1e-36 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA OS Mycobacterium tuberculosis GN tlyA PE 1 SV 2
blastp_uniprot_sprot sp|P19672|YQXC_BACSU 31 215 + 185 Gaps:11 67.62 281 40.00 4e-34 Putative rRNA methyltransferase YqxC OS Bacillus subtilis (strain 168) GN yqxC PE 3 SV 3
blastp_uniprot_sprot sp|Q06803|HLYA_BRAHO 34 215 + 182 Gaps:12 77.50 240 40.86 7e-31 Hemolysin A OS Brachyspira hyodysenteriae GN tlyA PE 2 SV 1
blastp_uniprot_sprot sp|Q8DEV0|RLUD_VIBVU 33 90 + 58 none 17.85 325 41.38 4e-06 Ribosomal large subunit pseudouridine synthase D OS Vibrio vulnificus (strain CMCP6) GN rluD PE 3 SV 1
rpsblast_cdd gnl|CDD|31382 31 216 + 186 Gaps:4 77.55 245 48.42 5e-51 COG1189 COG1189 Predicted rRNA methylase [Translation ribosomal structure and biogenesis].
rpsblast_cdd gnl|CDD|129570 34 216 + 183 Gaps:4 80.26 228 44.81 1e-40 TIGR00478 tly hemolysin TlyA family protein. Hemolysins are exotoxins that attack blood cell membranes and cause cell rupture often by forming a pore in the membrane. At least two members of this protein family have been characterized indirectly as pore-forming hemolysins one from the spirochete Serpula (Treponema) hyodysenteriae and one from Mycobacterium tuberculosis. However homology domains in this protein suggest methyltransferase activity (pfam01728) and RNA-binding activity (pfam01479).
rpsblast_cdd gnl|CDD|201939 89 204 + 116 Gaps:26 75.71 177 35.82 4e-16 pfam01728 FtsJ FtsJ-like methyltransferase. This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N terminus of flaviviral NS5 protein. It has been hypothesised that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping.
rpsblast_cdd gnl|CDD|183020 34 86 + 53 none 16.31 325 47.17 3e-09 PRK11180 rluD 23S rRNA pseudouridine synthase D Provisional.

15 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 32 87 56 SSF55174 none none none
Gene3D 119 202 84 G3DSA:3.40.50.150 none none IPR029063
PANTHER 25 215 191 PTHR32319:SF0 none none none
ProSiteProfiles 33 87 55 PS50889 none S4 RNA-binding domain profile. IPR002942
SUPERFAMILY 88 217 130 SSF53335 none none IPR029063
SMART 33 96 64 SM00363 none S4 RNA-binding domain IPR002942
Phobius 1 170 170 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 171 191 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 243 264 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 25 215 191 PTHR32319 none none none
Gene3D 32 118 87 G3DSA:3.10.290.10 none none IPR002942
Pfam 91 207 117 PF01728 none FtsJ-like methyltransferase IPR002877
Phobius 265 268 4 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Pfam 33 80 48 PF01479 none S4 domain IPR002942
Phobius 192 242 51 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none

0 Localization

0 Qtllist

0 Targeting