Protein : Qrob_P0318620.2 Q. robur
Protein Identifier  ? Qrob_P0318620.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=3) K12191 - charged multivesicular body protein 2A Gene Prediction Quality  validated
Protein length 

Sequence

Length: 224  
Kegg Orthology  K12191
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0 Synonyms

1 GO Terms

Identifier Name Description
GO:0007034 vacuolar transport The directed movement of substances into, out of or within a vacuole.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pvu:PHAVU_010G132400g 1 223 + 223 Gaps:2 100.00 225 88.44 6e-131 hypothetical protein
blastp_kegg lcl|atr:s00012p00151310 1 223 + 223 none 100.00 223 86.10 2e-128 AMTR_s00012p00151310 hypothetical protein
blastp_kegg lcl|cic:CICLE_v10009411mg 1 223 + 223 none 100.00 223 88.79 3e-128 hypothetical protein
blastp_kegg lcl|cit:102610845 1 223 + 223 none 100.00 223 88.79 3e-128 vacuolar protein sorting-associated protein 2 homolog 1-like
blastp_kegg lcl|cmo:103492353 1 223 + 223 none 100.00 223 87.00 3e-128 vacuolar protein sorting-associated protein 2 homolog 1
blastp_kegg lcl|csv:101205975 1 223 + 223 none 100.00 223 86.55 2e-127 vacuolar protein sorting-associated protein 2 homolog 1-like
blastp_kegg lcl|mus:103996837 1 223 + 223 none 100.00 223 86.55 2e-127 vacuolar protein sorting-associated protein 2 homolog 1
blastp_kegg lcl|mus:103987001 1 223 + 223 none 100.00 223 82.51 2e-126 vacuolar protein sorting-associated protein 2 homolog 1-like
blastp_kegg lcl|pop:POPTR_0001s17040g 1 223 + 223 Gaps:3 100.00 226 88.05 3e-126 POPTRDRAFT_829509 hypothetical protein
blastp_kegg lcl|mus:103986100 1 223 + 223 none 100.00 223 85.20 1e-125 vacuolar protein sorting-associated protein 2 homolog 1-like
blastp_pdb 3frv_A 4 149 + 146 Gaps:2 97.37 152 27.70 7e-11 mol:protein length:152 Charged multivesicular body protein 3
blastp_pdb 2gd5_D 9 184 + 176 Gaps:5 96.65 179 28.32 1e-10 mol:protein length:179 Charged multivesicular body protein 3
blastp_pdb 2gd5_C 9 184 + 176 Gaps:5 96.65 179 28.32 1e-10 mol:protein length:179 Charged multivesicular body protein 3
blastp_pdb 2gd5_B 9 184 + 176 Gaps:5 96.65 179 28.32 1e-10 mol:protein length:179 Charged multivesicular body protein 3
blastp_pdb 2gd5_A 9 184 + 176 Gaps:5 96.65 179 28.32 1e-10 mol:protein length:179 Charged multivesicular body protein 3
blastp_pdb 3frt_B 9 184 + 176 Gaps:5 79.36 218 28.32 2e-10 mol:protein length:218 Charged multivesicular body protein 3
blastp_pdb 3frt_A 9 184 + 176 Gaps:5 79.36 218 28.32 2e-10 mol:protein length:218 Charged multivesicular body protein 3
blastp_uniprot_sprot sp|Q9SKI2|VPS2A_ARATH 1 223 + 223 Gaps:1 99.56 225 86.16 1e-123 Vacuolar protein sorting-associated protein 2 homolog 1 OS Arabidopsis thaliana GN VPS2.1 PE 1 SV 2
blastp_uniprot_sprot sp|Q54DB1|CM2A2_DICDI 3 196 + 194 none 97.98 198 60.31 3e-82 Charged multivesicular body protein 2a homolog 2 OS Dictyostelium discoideum GN chmp2a2 PE 3 SV 1
blastp_uniprot_sprot sp|Q9DB34|CHM2A_MOUSE 1 189 + 189 Gaps:4 86.94 222 60.62 2e-68 Charged multivesicular body protein 2a OS Mus musculus GN Chmp2a PE 1 SV 1
blastp_uniprot_sprot sp|Q7ZW25|CHM2A_DANRE 1 222 + 222 Gaps:5 99.55 220 53.42 2e-68 Charged multivesicular body protein 2a OS Danio rerio GN chmp2a PE 2 SV 1
blastp_uniprot_sprot sp|O43633|CHM2A_HUMAN 1 185 + 185 none 83.33 222 61.08 4e-68 Charged multivesicular body protein 2a OS Homo sapiens GN CHMP2A PE 1 SV 1
blastp_uniprot_sprot sp|Q6IP52|CHM2A_XENLA 1 185 + 185 none 84.09 220 58.92 2e-66 Charged multivesicular body protein 2a OS Xenopus laevis GN chmp2a PE 2 SV 1
blastp_uniprot_sprot sp|Q6DFS6|CHM2A_XENTR 1 185 + 185 none 84.09 220 58.92 2e-66 Charged multivesicular body protein 2a OS Xenopus tropicalis GN chmp2a PE 2 SV 1
blastp_uniprot_sprot sp|Q5ZHN1|CHM2A_CHICK 1 185 + 185 none 84.09 220 56.76 4e-56 Charged multivesicular body protein 2a OS Gallus gallus GN CHMP2A PE 2 SV 1
blastp_uniprot_sprot sp|P36108|DID4_YEAST 3 222 + 220 Gaps:5 96.98 232 46.22 6e-55 DOA4-independent degradation protein 4 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN DID4 PE 1 SV 2
blastp_uniprot_sprot sp|Q941D5|VPS2C_ARATH 4 221 + 218 Gaps:10 99.05 210 44.23 4e-53 Vacuolar protein sorting-associated protein 2 homolog 3 OS Arabidopsis thaliana GN VPS2.3 PE 2 SV 1
rpsblast_cdd gnl|CDD|146145 17 187 + 171 Gaps:2 100.00 169 35.50 3e-33 pfam03357 Snf7 Snf7. This family of proteins are involved in protein sorting and transport from the endosome to the vacuole/lysosome in eukaryotic cells. Vacuoles/lysosomes play an important role in the degradation of both lipids and cellular proteins. In order to perform this degradative function vacuoles/lysosomes contain numerous hydrolases which have been transported in the form of inactive precursors via the biosynthetic pathway and are proteolytically activated upon delivery to the vacuole/lysosome. The delivery of transmembrane proteins such as activated cell surface receptors to the lumen of the vacuole/lysosome either for degradation/downregulation or in the case of hydrolases for proper localisation requires the formation of multivesicular bodies (MVBs). These late endosomal structures are formed by invaginating and budding of the limiting membrane into the lumen of the compartment. During this process a subset of the endosomal membrane proteins is sorted into the forming vesicles. Mature MVBs fuse with the vacuole/lysosome thereby releasing cargo containing vesicles into its hydrolytic lumen for degradation. Endosomal proteins that are not sorted into the intralumenal MVB vesicles are either recycled back to the plasma membrane or Golgi complex or remain in the limiting membrane of the MVB and are thereby transported to the limiting membrane of the vacuole/lysosome as a consequence of fusion. Therefore the MVB sorting pathway plays a critical role in the decision between recycling and degradation of membrane proteins. A few archaeal sequences are also present within this family.
rpsblast_cdd gnl|CDD|35050 36 223 + 188 Gaps:10 97.06 204 31.82 3e-10 COG5491 VPS24 Conserved protein implicated in secretion [Cell motility and secretion].
rpsblast_kog gnl|CDD|38440 4 223 + 220 Gaps:2 99.11 224 62.61 4e-65 KOG3230 KOG3230 KOG3230 Vacuolar assembly/sorting protein DID4 [Intracellular trafficking secretion and vesicular transport].

4 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 17 186 170 PF03357 none Snf7 IPR005024
PANTHER 2 223 222 PTHR10476 none none none
Coils 12 47 36 Coil none none none
PANTHER 2 223 222 PTHR10476:SF4 none none none

0 Localization

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC_3P Qrob_Chr05 5 s_2GDU0O_517 s_1BT8O3_239 25,81 0 55,45 lod 2,2101 5,5

0 Targeting