Protein : Qrob_P0311240.2 Q. robur
Protein Identifier  ? Qrob_P0311240.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=11) KOG1052//KOG1053//KOG1054//KOG1055//KOG1056//KOG4440 - Glutamate-gated kainate-type ion channel receptor subunit GluR5 and related subunits [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. // Glutamate-gated NMDA-type ion channel receptor subunit GRIN2A and related subunits [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. // Glutamate-gated AMPA-type ion channel receptor subunit GluR2 and related subunits [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. // GABA-B ion channel receptor subunit GABABR1 and related subunits G-protein coupled receptor superfamily [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. // Glutamate-gated metabotropic ion channel receptor subunit GRM2 and related subunits G-protein coupled receptor superfamily [Inorganic ion transport and metabolism Signal transduction mechanisms]. // NMDA selective glutamate-gated ion channel receptor subunit GRIN1 [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. Gene Prediction Quality  validated
Protein length 

Sequence

Length: 1861  
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

2 GO Terms

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0004970 ionotropic glutamate receptor activity Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.

40 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|mtr:MTR_2g015270 1 1517 + 1517 Gaps:270 94.28 1083 53.77 0.0 Glutamate receptor 2.7
blastp_kegg lcl|tcc:TCM_029764 1 1556 + 1556 Gaps:164 89.20 1111 60.75 0.0 Glutamate-gated kainate-type ion channel receptor subunit GluR5 putative
blastp_kegg lcl|rcu:RCOM_1012900 1 1476 + 1476 Gaps:111 93.12 843 62.42 0.0 glutamate receptor 2 plant putative
blastp_kegg lcl|pmum:103324853 1 1520 + 1520 Gaps:132 89.08 916 62.38 0.0 glutamate receptor 2.7-like
blastp_kegg lcl|pvu:PHAVU_006G179300g 1 1529 + 1529 Gaps:140 92.78 942 56.41 0.0 hypothetical protein
blastp_kegg lcl|gmx:100818619 1 1540 + 1540 Gaps:147 89.24 939 59.19 0.0 glutamate receptor 2.7-like
blastp_kegg lcl|tcc:TCM_029763 1 1534 + 1534 Gaps:149 90.86 919 59.88 0.0 Glutamate-gated kainate-type ion channel receptor subunit GluR5 putative
blastp_kegg lcl|cam:101492454 1 1518 + 1518 Gaps:130 90.50 905 59.10 0.0 glutamate receptor 2.7-like
blastp_kegg lcl|pop:POPTR_0004s05180g 1 1561 + 1561 Gaps:176 92.27 931 60.42 0.0 POPTRDRAFT_817827 hypothetical protein
blastp_kegg lcl|gmx:100818078 1 1541 + 1541 Gaps:165 92.16 918 56.74 0.0 glutamate receptor 2.7-like
blastp_pdb 3kg2_D 419 1475 + 1057 Gaps:210 69.26 823 26.49 1e-13 mol:protein length:823 Glutamate receptor 2
blastp_pdb 3kg2_C 419 1475 + 1057 Gaps:210 69.26 823 26.49 1e-13 mol:protein length:823 Glutamate receptor 2
blastp_pdb 3kg2_B 419 1475 + 1057 Gaps:210 69.26 823 26.49 1e-13 mol:protein length:823 Glutamate receptor 2
blastp_pdb 3kg2_A 419 1475 + 1057 Gaps:210 69.26 823 26.49 1e-13 mol:protein length:823 Glutamate receptor 2
blastp_uniprot_sprot sp|Q9LFN8|GLR26_ARATH 5 1475 + 1471 Gaps:234 83.87 967 37.48 7e-110 Glutamate receptor 2.6 OS Arabidopsis thaliana GN GLR2.6 PE 2 SV 2
blastp_uniprot_sprot sp|Q9LFN5|GLR25_ARATH 5 1475 + 1471 Gaps:220 86.71 918 36.31 1e-109 Glutamate receptor 2.5 OS Arabidopsis thaliana GN GLR2.5 PE 2 SV 2
blastp_uniprot_sprot sp|Q8LGN0|GLR27_ARATH 1 1476 + 1476 Gaps:209 83.19 952 36.36 2e-107 Glutamate receptor 2.7 OS Arabidopsis thaliana GN GLR2.7 PE 2 SV 3
blastp_uniprot_sprot sp|O81078|GLR29_ARATH 5 1532 + 1528 Gaps:230 87.66 940 37.50 5e-104 Glutamate receptor 2.9 OS Arabidopsis thaliana GN GLR2.9 PE 2 SV 1
blastp_uniprot_sprot sp|O81776|GLR24_ARATH 5 1463 + 1459 Gaps:206 83.93 896 38.03 2e-103 Glutamate receptor 2.4 OS Arabidopsis thaliana GN GLR2.4 PE 2 SV 2
blastp_uniprot_sprot sp|Q93YT1|GLR32_ARATH 1 1475 + 1475 Gaps:238 89.91 912 36.22 2e-102 Glutamate receptor 3.2 OS Arabidopsis thaliana GN GLR3.2 PE 1 SV 2
blastp_uniprot_sprot sp|Q9SW97|GLR35_ARATH 4 1475 + 1472 Gaps:219 84.89 953 36.96 1e-101 Glutamate receptor 3.5 OS Arabidopsis thaliana GN GLR3.5 PE 2 SV 2
blastp_uniprot_sprot sp|Q84W41|GLR36_ARATH 42 1475 + 1434 Gaps:231 87.26 903 36.04 1e-99 Glutamate receptor 3.6 OS Arabidopsis thaliana GN GLR3.6 PE 2 SV 1
blastp_uniprot_sprot sp|Q9C5V5|GLR28_ARATH 5 1476 + 1472 Gaps:202 86.91 947 35.12 5e-97 Glutamate receptor 2.8 OS Arabidopsis thaliana GN GLR2.8 PE 2 SV 2
blastp_uniprot_sprot sp|Q8GXJ4|GLR34_ARATH 14 1475 + 1462 Gaps:259 85.51 959 35.37 2e-96 Glutamate receptor 3.4 OS Arabidopsis thaliana GN GLR3.4 PE 2 SV 2
rpsblast_cdd gnl|CDD|107361 1 1115 + 1115 Gaps:98 93.43 350 39.14 3e-64 cd06366 PBP1_GABAb_receptor Ligand-binding domain of GABAb receptors which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). Ligand-binding domain of GABAb receptors which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and like glutamate and other transmitters acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha_i proteins and activation causes a decrease in calcium an increase in potassium membrane conductance and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release for example.
rpsblast_cdd gnl|CDD|189368 469 1475 + 1007 Gaps:67 98.88 268 32.83 1e-36 pfam00060 Lig_chan Ligand-gated ion channel. This family includes the four transmembrane regions of the ionotropic glutamate receptors and NMDA receptors.
rpsblast_cdd gnl|CDD|178749 1549 1782 + 234 Gaps:58 27.93 1153 42.24 3e-30 PLN03210 PLN03210 Resistant to P. syringae 6 Provisional.
rpsblast_cdd gnl|CDD|201592 1 1081 + 1081 Gaps:58 98.54 343 28.40 8e-30 pfam01094 ANF_receptor Receptor family ligand binding region. This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
rpsblast_cdd gnl|CDD|153138 1 1043 + 1043 Gaps:79 78.16 348 27.21 2e-26 cd06350 PBP1_GPCR_family_C_like Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). The metabotropic glutamate receptors (mGluR) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. The mGluRs are coupled to G proteins and are thus distinct from the iGluRs which internally contain ligand-gated ion channels. The mGluR structure is divided into three regions: the extracellular region the seven-spanning transmembrane region and the cytoplasmic region. The extracellular region is further devided into the ligand-binding domain (LBD) and the cysteine-rich domain. The LBD has sequence similarity to the LIVBP which is a bacterial periplasmic protein (PBP) as well as to the extracellular region of both iGluR and the gamma-aminobutyric acid (GABA)b receptor. iGluRs are divided into three main subtypes based on pharmacological profile: NMDA AMPA and kainate receptors. All family C GPCRs have a large extracellular N terminus that contain a domain with homology to bacterial periplasmic amino acid-binding proteins.
rpsblast_cdd gnl|CDD|153137 1 1024 + 1024 Gaps:41 86.91 298 25.48 9e-22 cd06269 PBP1_glutamate_receptors_like Family C G-protein couples receptors (GPCRs) membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs) and the N-terminal leucine/isoleucine/valine- binding protein (LIVBP)-like domain of the ionotropic glutamate receptors. This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs) membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs) and the N-terminal leucine/isoleucine/valine- binding protein (LIVBP)-like domain of the ionotropic glutamate receptors all of which are structurally similar and related to the periplasmic-binding fold type I family. The family C GPCRs consist of metabotropic glutamate receptor (mGluR) receptors a calcium-sensing receptor (CaSR) gamma-aminobutyric receptors (GABAb) the promiscuous L-alpha-amino acid receptor GPR6A families of taste and pheromone receptors and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids ions and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors AMPA receptors and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B) the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E GC-F) and olfactory receptors (GC-D and GC-G).

45 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 488 498 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 551 703 153 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 499 520 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 521 525 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 704 726 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Gene3D 100 241 142 G3DSA:3.40.50.2300 none none none
Gene3D 859 1025 167 G3DSA:3.40.50.2300 none none none
Phobius 1306 1860 555 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
SUPERFAMILY 1336 1447 112 SSF53850 none none none
SUPERFAMILY 1158 1260 103 SSF53850 none none none
PANTHER 359 737 379 PTHR18966:SF6 none none none
SUPERFAMILY 799 1109 311 SSF53822 none none IPR028082
Pfam 414 678 265 PF00497 none Bacterial extracellular solute-binding proteins, family 3 none
Pfam 1158 1447 290 PF00497 none Bacterial extracellular solute-binding proteins, family 3 none
Phobius 1275 1285 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 526 550 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1256 1274 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1 466 466 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
SMART 1138 1448 311 SM00079 none Eukaryotic homologues of bacterial periplasmic substrate binding proteins. IPR001320
Pfam 1 322 322 PF01094 none Receptor family ligand binding region IPR001828
Pfam 797 1088 292 PF01094 none Receptor family ligand binding region IPR001828
SUPERFAMILY 570 677 108 SSF53850 none none none
SUPERFAMILY 353 471 119 SSF53850 none none none
Gene3D 1405 1446 42 G3DSA:3.40.190.10 none none none
Gene3D 639 678 40 G3DSA:3.40.190.10 none none none
Gene3D 1151 1231 81 G3DSA:3.40.190.10 none none none
Gene3D 400 442 43 G3DSA:3.40.190.10 none none none
Gene3D 1246 1305 60 G3DSA:1.10.287.70 none none none
Gene3D 1306 1358 53 G3DSA:1.10.287.70 none none none
Gene3D 457 590 134 G3DSA:1.10.287.70 none none none

6 Localization

Analysis Start End Length
TMHMM 1255 1274 19
TMHMM 1294 1316 22
TMHMM 507 524 17
TMHMM 470 487 17
TMHMM 528 550 22
TMHMM 703 725 22

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_rEpiBC_3P Qrob_Chr05 5 s_2GDU0O_517 s_1BT8O3_239 25,81 0 55,45 lod 2,2101 5,5

0 Targeting