Protein : Qrob_P0224090.2 Q. robur
Protein Identifier  ? Qrob_P0224090.2 Organism . Name  Quercus robur
Score  98.0 Score Type  egn
Protein Description  (M=1) K06126 - ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-] Gene Prediction Quality  validated
Protein length 

Sequence

Length: 506  
Kegg Orthology  K06126
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0050660 flavin adenine dinucleotide binding Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
GO:0006744 ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

32 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_020380 18 505 + 488 Gaps:30 90.87 504 79.26 0.0 FAD/NAD(P)-binding oxidoreductase family protein isoform 1
blastp_kegg lcl|pmum:103337611 7 505 + 499 Gaps:32 91.57 510 77.94 0.0 ubiquinone biosynthesis monooxygenase COQ6
blastp_kegg lcl|pper:PRUPE_ppa004239mg 7 505 + 499 Gaps:32 89.64 521 78.16 0.0 hypothetical protein
blastp_kegg lcl|rcu:RCOM_1020470 8 505 + 498 Gaps:30 90.87 515 76.92 0.0 monoxygenase putative
blastp_kegg lcl|pxb:103927298 9 505 + 497 Gaps:32 91.18 510 77.42 0.0 ubiquinone biosynthesis monooxygenase COQ6
blastp_kegg lcl|vvi:100248856 4 498 + 495 Gaps:35 88.00 525 78.35 0.0 ubiquinone biosynthesis monooxygenase COQ6-like
blastp_kegg lcl|pop:POPTR_0001s14360g 13 505 + 493 Gaps:30 90.25 513 78.19 0.0 POPTRDRAFT_1066008 hypothetical protein
blastp_kegg lcl|fve:101298602 4 505 + 502 Gaps:32 92.34 509 76.17 0.0 ubiquinone biosynthesis monooxygenase COQ6-like
blastp_kegg lcl|mdm:103451859 13 505 + 493 Gaps:33 90.37 509 77.83 0.0 ubiquinone biosynthesis monooxygenase COQ6
blastp_kegg lcl|cit:102630098 69 503 + 435 none 84.47 515 79.77 0.0 ubiquinone biosynthesis monooxygenase COQ6-like
blastp_uniprot_sprot sp|Q6DF46|COQ6_XENTR 20 496 + 477 Gaps:65 93.10 464 36.81 1e-80 Ubiquinone biosynthesis monooxygenase COQ6 OS Xenopus tropicalis GN coq6 PE 2 SV 1
blastp_uniprot_sprot sp|Q9Y2Z9|COQ6_HUMAN 103 496 + 394 Gaps:20 81.62 468 36.91 1e-76 Ubiquinone biosynthesis monooxygenase COQ6 OS Homo sapiens GN COQ6 PE 1 SV 2
blastp_uniprot_sprot sp|F1RAX8|COQ6_DANRE 3 496 + 494 Gaps:53 92.77 484 35.63 5e-76 Ubiquinone biosynthesis monooxygenase COQ6 OS Danio rerio GN coq6 PE 2 SV 1
blastp_uniprot_sprot sp|Q8R1S0|COQ6_MOUSE 103 496 + 394 Gaps:20 80.25 476 37.17 1e-75 Ubiquinone biosynthesis monooxygenase COQ6 OS Mus musculus GN Coq6 PE 2 SV 3
blastp_uniprot_sprot sp|Q68FU7|COQ6_RAT 103 496 + 394 Gaps:20 80.25 476 37.96 5e-75 Ubiquinone biosynthesis monooxygenase COQ6 OS Rattus norvegicus GN Coq6 PE 2 SV 1
blastp_uniprot_sprot sp|Q2KIL4|COQ6_BOVIN 103 496 + 394 Gaps:20 81.45 469 37.43 1e-74 Ubiquinone biosynthesis monooxygenase COQ6 OS Bos taurus GN COQ6 PE 2 SV 2
blastp_uniprot_sprot sp|O01884|COQ6_CAEEL 15 499 + 485 Gaps:64 97.34 451 32.80 4e-62 Probable ubiquinone biosynthesis monooxygenase coq-6 OS Caenorhabditis elegans GN coq-6 PE 3 SV 2
blastp_uniprot_sprot sp|Q54EN1|COQ6_DICDI 74 501 + 428 Gaps:41 87.07 495 30.86 7e-58 Ubiquinone biosynthesis monooxygenase COQ6 homolog OS Dictyostelium discoideum GN coq6 PE 3 SV 1
blastp_uniprot_sprot sp|P25535|UBII_ECOLI 17 502 + 486 Gaps:94 99.00 400 35.35 1e-56 2-octaprenylphenol hydroxylase OS Escherichia coli (strain K12) GN ubiI PE 1 SV 2
blastp_uniprot_sprot sp|Q9VMQ5|COQ6_DROME 94 498 + 405 Gaps:41 81.34 477 31.96 6e-56 Putative ubiquinone biosynthesis monooxygenase COQ6 OS Drosophila melanogaster GN CG7277 PE 2 SV 1
rpsblast_cdd gnl|CDD|162643 20 492 + 473 Gaps:52 100.00 437 44.62 1e-133 TIGR01989 COQ6 ubiquinone biosynthesis monooxygenase COQ6. This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone.
rpsblast_cdd gnl|CDD|200149 21 497 + 477 Gaps:92 100.00 387 41.34 1e-114 TIGR01988 Ubi-OHases Ubiquinone biosynthesis hydroxylase UbiH/UbiF/VisC/COQ6 family. This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases as yet undiscovered are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described UbiB (which acts first at position 6 see TIGR01982) UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly E. coli contains another hydroxylase gene called visC that is highly similar to UbiF adjacent to UbiH and when mutated results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH but also possess a non-orthologous gene COQ7 which complements UbiF.
rpsblast_cdd gnl|CDD|181199 15 497 + 483 Gaps:105 99.74 391 35.90 2e-64 PRK08020 ubiF 2-octaprenyl-3-methyl-6-methoxy-1 4-benzoquinol hydroxylase Reviewed.
rpsblast_cdd gnl|CDD|181565 17 497 + 481 Gaps:103 96.30 405 36.41 1e-63 PRK08850 PRK08850 2-octaprenyl-6-methoxyphenol hydroxylase Validated.
rpsblast_cdd gnl|CDD|168201 19 478 + 460 Gaps:102 92.35 405 38.77 3e-61 PRK05714 PRK05714 2-octaprenyl-3-methyl-6-methoxy-1 4-benzoquinol hydroxylase Provisional.
rpsblast_cdd gnl|CDD|162640 21 497 + 477 Gaps:99 100.00 382 33.25 6e-61 TIGR01984 UbiH 2-polyprenyl-6-methoxyphenol 4-hydroxylase. This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype.
rpsblast_cdd gnl|CDD|30999 18 497 + 480 Gaps:100 99.22 387 33.33 6e-58 COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].
rpsblast_cdd gnl|CDD|180946 20 489 + 470 Gaps:105 90.84 415 35.01 6e-57 PRK07364 PRK07364 2-octaprenyl-6-methoxyphenyl hydroxylase Validated.
rpsblast_cdd gnl|CDD|181564 17 497 + 481 Gaps:102 99.74 384 35.51 1e-56 PRK08849 PRK08849 2-octaprenyl-3-methyl-6-methoxy-1 4-benzoquinol hydroxylase Provisional.
rpsblast_cdd gnl|CDD|180935 20 497 + 478 Gaps:120 96.28 403 36.86 2e-56 PRK07333 PRK07333 2-octaprenyl-6-methoxyphenyl hydroxylase Provisional.

17 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
TIGRFAM 67 497 431 TIGR01988 "UniPathway:UPA00232" Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family IPR010971
Gene3D 18 69 52 G3DSA:3.40.50.720 none none IPR016040
PANTHER 1 40 40 PTHR13789:SF5 none none none
PANTHER 71 499 429 PTHR13789:SF5 none none none
SUPERFAMILY 374 490 117 SSF51905 none none none
SUPERFAMILY 76 251 176 SSF51905 none none none
PRINTS 230 245 16 PR00420 none Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature none
PRINTS 387 402 16 PR00420 none Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature none
PRINTS 21 43 23 PR00420 none Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature none
PRINTS 402 418 17 PR00420 none Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature none
Pfam 372 448 77 PF01494 none FAD binding domain IPR002938
Pfam 228 325 98 PF01494 none FAD binding domain IPR002938
ProSitePatterns 401 414 14 PS01304 "UniPathway:UPA00232" ubiH/COQ6 monooxygenase family signature. IPR018168
Gene3D 375 463 89 G3DSA:3.50.50.60 none none none
Gene3D 75 256 182 G3DSA:3.50.50.60 none none none
PANTHER 71 499 429 PTHR13789 none none none
PANTHER 1 40 40 PTHR13789 none none none

1 Localization

Analysis Start End Length
TMHMM 21 43 22

0 Qtllist

0 Targeting