Protein : Qrob_P0202090.2 Q. robur
Protein Identifier  ? Qrob_P0202090.2 Organism . Name  Quercus robur
Score  64.0 Score Type  egn
Protein Description  (M=1) PTHR13058 - THREE PRIME REPAIR EXONUCLEASE 1, 2 Code Enzyme  EC:2.7.7.7
Gene Prediction Quality  validated Protein length 

Sequence

Length: 336  
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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0003676 nucleic acid binding Interacting selectively and non-covalently with any nucleic acid.
GO:0004527 exonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.

35 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_1434480 1 332 + 332 Gaps:2 99.40 334 65.96 1e-149 exonuclease putative (EC:2.7.7.7)
blastp_kegg lcl|vvi:100264957 1 333 + 333 Gaps:3 99.70 337 63.99 4e-149 DNA polymerase III polC-type-like
blastp_kegg lcl|cit:102613049 1 325 + 325 Gaps:9 94.99 339 67.08 1e-143 uncharacterized LOC102613049
blastp_kegg lcl|pop:POPTR_0005s02060g 1 332 + 332 Gaps:1 98.81 337 63.36 2e-143 hypothetical protein
blastp_kegg lcl|cic:CICLE_v10001747mg 1 325 + 325 Gaps:9 94.99 339 66.46 1e-142 hypothetical protein
blastp_kegg lcl|tcc:TCM_026731 1 320 + 320 Gaps:2 95.27 338 63.35 4e-142 DNA polymerase III polC-type putative isoform 1
blastp_kegg lcl|pper:PRUPE_ppa008284mg 1 335 + 335 Gaps:3 100.00 338 60.95 5e-138 hypothetical protein
blastp_kegg lcl|mtr:MTR_7g112320 1 332 + 332 Gaps:4 98.80 332 60.67 8e-138 DNA polymerase III polC-type
blastp_kegg lcl|pvu:PHAVU_001G226600g 1 332 + 332 Gaps:5 98.79 331 61.77 2e-137 hypothetical protein
blastp_kegg lcl|gmx:100807346 1 332 + 332 Gaps:6 99.09 329 63.19 8e-137 three prime repair exonuclease 2-like
blastp_pdb 1y97_B 132 327 + 196 Gaps:32 94.12 238 26.34 3e-07 mol:protein length:238 Three prime repair exonuclease 2
blastp_pdb 1y97_A 132 327 + 196 Gaps:32 94.12 238 26.34 3e-07 mol:protein length:238 Three prime repair exonuclease 2
blastp_pdb 2p1j_B 132 234 + 103 Gaps:15 51.61 186 38.54 5e-07 mol:protein length:186 DNA polymerase III polC-type
blastp_pdb 2p1j_A 132 234 + 103 Gaps:15 51.61 186 38.54 5e-07 mol:protein length:186 DNA polymerase III polC-type
blastp_uniprot_sprot sp|Q10384|Y2191_MYCTU 132 324 + 193 Gaps:29 29.46 645 34.74 6e-14 Uncharacterized protein Rv2191/MT2247 OS Mycobacterium tuberculosis GN Rv2191 PE 4 SV 1
blastp_uniprot_sprot sp|Q8EQU6|DPO3_OCEIH 132 306 + 175 Gaps:19 11.34 1428 38.27 7e-14 DNA polymerase III PolC-type OS Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) GN polC PE 3 SV 1
blastp_uniprot_sprot sp|Q895K2|DPO3_CLOTE 132 302 + 171 Gaps:28 11.00 1427 37.58 1e-13 DNA polymerase III PolC-type OS Clostridium tetani (strain Massachusetts / E88) GN polC PE 3 SV 1
blastp_uniprot_sprot sp|Q8RA32|DPO3_THETN 134 294 + 161 Gaps:24 10.49 1401 40.14 7e-13 DNA polymerase III PolC-type OS Thermoanaerobacter tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) GN polC PE 3 SV 1
blastp_uniprot_sprot sp|Q8XJR3|DPO3_CLOPE 134 302 + 169 Gaps:20 10.70 1449 36.77 2e-12 DNA polymerase III PolC-type OS Clostridium perfringens (strain 13 / Type A) GN polC PE 3 SV 1
blastp_uniprot_sprot sp|P13267|DPO3_BACSU 71 305 + 235 Gaps:38 16.08 1437 33.77 8e-11 DNA polymerase III PolC-type OS Bacillus subtilis (strain 168) GN polC PE 1 SV 2
blastp_uniprot_sprot sp|Q5HPS7|DPO3_STAEQ 131 310 + 180 Gaps:19 11.61 1438 31.74 4e-10 DNA polymerase III PolC-type OS Staphylococcus epidermidis (strain ATCC 35984 / RP62A) GN polC PE 3 SV 2
blastp_uniprot_sprot sp|Q8CPG6|DPO3_STAES 131 310 + 180 Gaps:19 11.58 1442 31.74 4e-10 DNA polymerase III PolC-type OS Staphylococcus epidermidis (strain ATCC 12228) GN polC PE 3 SV 1
blastp_uniprot_sprot sp|P63982|DPO3_STAAN 132 310 + 179 Gaps:19 11.54 1438 31.93 7e-10 DNA polymerase III PolC-type OS Staphylococcus aureus (strain N315) GN polC PE 1 SV 1
blastp_uniprot_sprot sp|P63981|DPO3_STAAM 132 310 + 179 Gaps:19 11.54 1438 31.93 7e-10 DNA polymerase III PolC-type OS Staphylococcus aureus (strain Mu50 / ATCC 700699) GN polC PE 3 SV 1
rpsblast_cdd gnl|CDD|176648 134 302 + 169 Gaps:19 99.37 159 41.77 1e-32 cd06127 DEDDh DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases part of the DnaQ-like (or DEDD) exonuclease superfamily catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III the main replicating enzyme in bacteria which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T Oligoribonuclease and RNA exonuclease (REX) among others.
rpsblast_cdd gnl|CDD|197752 132 302 + 171 Gaps:16 95.27 169 35.40 2e-30 smart00479 EXOIII exonuclease domain in DNA-polymerase alpha and epsilon chain ribonuclease T and other exonucleases.
rpsblast_cdd gnl|CDD|181157 131 305 + 175 Gaps:21 30.16 557 40.48 8e-27 PRK07883 PRK07883 hypothetical protein Validated.
rpsblast_cdd gnl|CDD|31188 132 306 + 175 Gaps:19 68.31 243 39.76 1e-22 COG0847 DnaQ DNA polymerase III epsilon subunit and related 3'-5' exonucleases [DNA replication recombination and repair].
rpsblast_cdd gnl|CDD|180524 132 298 + 167 Gaps:18 65.95 232 39.22 6e-21 PRK06309 PRK06309 DNA polymerase III subunit epsilon Validated.
rpsblast_cdd gnl|CDD|201510 134 295 + 162 Gaps:18 95.65 161 35.71 1e-20 pfam00929 RNase_T Exonuclease. This family includes a variety of exonuclease proteins such as ribonuclease T and the epsilon subunit of DNA polymerase III. .

6 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 100 325 226 PTHR13058 none none none
SUPERFAMILY 130 305 176 SSF53098 none none IPR012337
Gene3D 131 305 175 G3DSA:3.30.420.10 none none IPR012337
Pfam 134 295 162 PF00929 none Exonuclease IPR013520
SMART 132 311 180 SM00479 none none IPR006055
PANTHER 100 325 226 PTHR13058:SF14 none none none

0 Localization

0 Qtllist

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 44   Mitochondrion 2 0.109 0.737 NON-PLANT 44