Protein : Qrob_P0163760.2 Q. robur
Protein Identifier  ? Qrob_P0163760.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K03237 - translation initiation factor eIF-2 alpha subunit Gene Prediction Quality  validated
Protein length 

Sequence

Length: 279  
Kegg Orthology  K03237
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

4 GO Terms

Identifier Name Description
GO:0003723 RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
GO:0003676 nucleic acid binding Interacting selectively and non-covalently with any nucleic acid.
GO:0003743 translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
GO:0005850 eukaryotic translation initiation factor 2 complex Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|obr:102718759 6 275 + 270 Gaps:65 98.81 337 50.75 8e-84 eukaryotic translation initiation factor 2 subunit alpha-like
blastp_kegg lcl|pop:POPTR_0008s07250g 1 278 + 278 Gaps:1 62.97 343 87.96 3e-80 POPTRDRAFT_832599 hypothetical protein
blastp_kegg lcl|csv:101209681 1 278 + 278 Gaps:2 63.08 344 92.17 3e-79 eukaryotic translation initiation factor 2 subunit alpha-like
blastp_kegg lcl|fve:101313931 1 275 + 275 Gaps:1 63.34 341 86.57 3e-79 eukaryotic translation initiation factor 2 subunit alpha-like
blastp_kegg lcl|gmx:100815696 6 278 + 273 Gaps:1 63.53 340 91.67 8e-79 eukaryotic translation initiation factor 2 subunit alpha-like
blastp_kegg lcl|cic:CICLE_v10031993mg 1 274 + 274 none 62.50 344 90.70 1e-78 hypothetical protein
blastp_kegg lcl|cit:102615936 1 274 + 274 none 62.50 344 90.70 1e-78 eukaryotic translation initiation factor 2 subunit alpha-like
blastp_kegg lcl|gmx:100805950 6 278 + 273 Gaps:1 63.53 340 91.20 3e-78 eukaryotic translation initiation factor 2 subunit alpha-like
blastp_kegg lcl|rcu:RCOM_0494110 1 275 + 275 none 62.79 344 90.28 3e-78 eukaryotic translation initiation factor putative
blastp_kegg lcl|tcc:TCM_016157 6 278 + 273 Gaps:2 62.35 340 92.45 5e-78 Eukaryotic translation initiation factor 2 subunit 1
blastp_pdb 1q8k_A 8 255 + 248 Gaps:6 67.21 308 46.86 4e-28 mol:protein length:308 Eukaryotic translation initiation factor 2 su
blastp_pdb 1kl9_A 6 68 + 63 none 34.62 182 69.84 1e-23 mol:protein length:182 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SU
blastp_pdb 1q46_A 9 68 + 60 none 34.29 175 70.00 6e-22 mol:protein length:175 translation initiation factor 2 alpha subunit
blastp_pdb 2a1a_A 9 68 + 60 none 34.29 175 70.00 7e-22 mol:protein length:175 Eukaryotic translation initiation factor 2 al
blastp_pdb 2a19_A 9 68 + 60 none 34.29 175 70.00 7e-22 mol:protein length:175 Eukaryotic translation initiation factor 2 al
blastp_uniprot_sprot sp|P56286|IF2A_SCHPO 10 260 + 251 Gaps:46 97.06 306 37.71 8e-55 Eukaryotic translation initiation factor 2 subunit alpha OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN tif211 PE 1 SV 1
blastp_uniprot_sprot sp|P20459|IF2A_YEAST 10 235 + 226 Gaps:45 89.14 304 37.27 2e-48 Eukaryotic translation initiation factor 2 subunit alpha OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN SUI2 PE 1 SV 1
blastp_uniprot_sprot sp|Q869N9|IF2A_DICDI 9 250 + 242 Gaps:63 89.44 341 32.13 1e-38 Eukaryotic translation initiation factor 2 subunit 1 OS Dictyostelium discoideum GN eif2s1 PE 1 SV 1
blastp_uniprot_sprot sp|Q6GL89|IF2A_XENTR 6 262 + 257 none 61.59 315 51.55 4e-31 Eukaryotic translation initiation factor 2 subunit 1 OS Xenopus tropicalis GN eif2s1 PE 2 SV 1
blastp_uniprot_sprot sp|Q7ZTK4|IF2A_XENLA 6 262 + 257 none 61.59 315 51.03 1e-30 Eukaryotic translation initiation factor 2 subunit 1 OS Xenopus laevis GN eif2s1 PE 2 SV 1
blastp_uniprot_sprot sp|Q5ZLX2|IF2A_CHICK 6 262 + 257 none 61.59 315 50.52 3e-30 Eukaryotic translation initiation factor 2 subunit 1 OS Gallus gallus GN EIF2S1 PE 2 SV 2
blastp_uniprot_sprot sp|P05198|IF2A_HUMAN 6 262 + 257 none 61.59 315 50.52 6e-30 Eukaryotic translation initiation factor 2 subunit 1 OS Homo sapiens GN EIF2S1 PE 1 SV 3
blastp_uniprot_sprot sp|Q5R493|IF2A_PONAB 6 262 + 257 none 61.59 315 50.52 6e-30 Eukaryotic translation initiation factor 2 subunit 1 OS Pongo abelii GN EIF2S1 PE 2 SV 1
blastp_uniprot_sprot sp|P68101|IF2A_RAT 6 262 + 257 none 61.59 315 50.52 6e-30 Eukaryotic translation initiation factor 2 subunit 1 OS Rattus norvegicus GN Eif2s1 PE 1 SV 2
blastp_uniprot_sprot sp|Q6ZWX6|IF2A_MOUSE 6 262 + 257 none 61.59 315 50.52 6e-30 Eukaryotic translation initiation factor 2 subunit 1 OS Mus musculus GN Eif2s1 PE 1 SV 3
rpsblast_cdd gnl|CDD|185526 4 263 + 260 Gaps:1 61.44 319 45.41 7e-29 PTZ00248 PTZ00248 eukaryotic translation initiation factor 2 subunit 1 Provisional.
rpsblast_cdd gnl|CDD|203676 133 196 + 64 none 57.14 112 51.56 7e-23 pfam07541 EIF_2_alpha Eukaryotic translation initiation factor 2 alpha subunit. These proteins share a region of similarity that falls towards the C terminus from pfam00575.
rpsblast_cdd gnl|CDD|31290 10 232 + 223 none 60.97 269 32.32 3e-17 COG1093 SUI2 Translation initiation factor 2 alpha subunit (eIF-2alpha) [Translation ribosomal structure and biogenesis].
rpsblast_cdd gnl|CDD|88418 18 68 + 51 none 67.11 76 72.55 4e-16 cd04452 S1_IF2_alpha S1_IF2_alpha: The alpha subunit of translation Initiation Factor 2 S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. Eukaryotic and archaeal Initiation Factor 2 (e- and aIF2 respectively) are heterotrimeric proteins with three subunits (alpha beta and gamma). IF2 plays a crucial role in the process of translation initiation. The IF2 gamma subunit contains a GTP-binding site. The IF2 beta and gamma subunits together are thought to be responsible for binding methionyl-initiator tRNA. The ternary complex consisting of IF2 GTP and the methionyl-initiator tRNA binds to the small subunit of the ribosome as part of a pre-initiation complex that scans the mRNA to find the AUG start codon. The IF2-bound GTP is hydrolyzed to GDP when the methionyl-initiator tRNA binds the AUG start codon at which time the IF2 is released with its bound GDP. The large ribosomal subunit then joins with the small subunit to complete the initiation complex which is competent to begin translation. The IF2a subunit is a major site of control of the translation initiation process via phosphorylation of a specific serine residue. This alpha subunit is well conserved in eukaryotes and archaea but is not present in bacteria. IF2 is a cold-shock-inducible protein..
rpsblast_cdd gnl|CDD|179696 17 68 + 52 none 19.85 262 34.62 2e-07 PRK03987 PRK03987 translation initiation factor IF-2 subunit alpha Validated.

12 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 10 67 58 G3DSA:2.40.50.140 none none IPR012340
Gene3D 140 262 123 G3DSA:3.30.70.1130 none none IPR024055
PANTHER 2 278 277 PTHR10602:SF0 none none none
SUPERFAMILY 10 68 59 SSF50249 none none IPR012340
Phobius 1 111 111 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 112 132 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Pfam 128 196 69 PF07541 none Eukaryotic translation initiation factor 2 alpha subunit IPR011488
Coils 238 263 26 Coil none none none
SUPERFAMILY 139 255 117 SSF110993 none none IPR024055
Phobius 133 278 146 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Pfam 19 68 50 PF00575 none S1 RNA binding domain IPR003029
PANTHER 2 278 277 PTHR10602 none none none

1 Localization

Analysis Start End Length
TMHMM 110 132 22

4 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2003_QTL11_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 4,16 48,16 lod 2,3 5,1
Bourran2_2004_QTL12_peak_Bud_burst_3P Qrob_Chr09 9 s_1BDO6G_250 s_1A83AM_496 34,31 9,31 44,31 lod 3,6 7,6
PM_1999_QTL15_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 9,16 47,16 lod 3,6 6,5
Bourran1_2003_QTL5_peak_Bud_burst_3P Qrob_Chr09 9 s_1ATM17_504 s_1AYZFM_899 29,81 19,81 41,81 lod 3,3 8,9

0 Targeting