Protein : Qrob_P0123910.2 Q. robur
Protein Identifier  ? Qrob_P0123910.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=14) 4.2.1.78 - (S)-norcoclaurine synthase. Code Enzyme  EC:4.2.1.78
Gene Prediction Quality  validated Protein length 

Sequence

Length: 138  
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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0006952 defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.

25 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|gmx:100305838 2 135 + 134 Gaps:1 83.85 161 67.41 4e-52 uncharacterized LOC100305838
blastp_kegg lcl|cam:101513514 2 135 + 134 Gaps:1 83.85 161 62.96 2e-51 S-norcoclaurine synthase-like
blastp_kegg lcl|cic:CICLE_v10022655mg 2 132 + 131 Gaps:2 84.52 155 63.36 1e-49 hypothetical protein
blastp_kegg lcl|cit:102624226 2 132 + 131 Gaps:2 84.52 155 63.36 1e-49 S-norcoclaurine synthase-like
blastp_kegg lcl|cic:CICLE_v10012995mg 2 131 + 130 Gaps:2 83.87 155 63.85 3e-49 hypothetical protein
blastp_kegg lcl|pvu:PHAVU_011G019300g 2 135 + 134 Gaps:7 83.85 161 62.22 5e-49 hypothetical protein
blastp_kegg lcl|cit:102609489 2 131 + 130 Gaps:2 83.87 155 63.08 1e-48 S-norcoclaurine synthase-like
blastp_kegg lcl|vvi:100242527 2 133 + 132 Gaps:3 82.32 164 56.30 3e-44 S-norcoclaurine synthase-like
blastp_kegg lcl|csv:101224667 2 134 + 133 Gaps:2 84.71 157 54.14 4e-41 S-norcoclaurine synthase-like
blastp_kegg lcl|csv:101218487 2 134 + 133 Gaps:2 84.71 157 54.14 4e-41 S-norcoclaurine synthase-like
blastp_pdb 2vq5_B 4 136 + 133 Gaps:4 67.16 201 42.22 8e-23 mol:protein length:201 S-NORCOCLAURINE SYNTHASE
blastp_pdb 2vq5_A 4 136 + 133 Gaps:4 67.16 201 42.22 8e-23 mol:protein length:201 S-NORCOCLAURINE SYNTHASE
blastp_pdb 2vne_B 4 136 + 133 Gaps:4 67.16 201 42.22 8e-23 mol:protein length:201 S-NORCOCLAURINE SYNTHASE
blastp_pdb 2vne_A 4 136 + 133 Gaps:4 67.16 201 42.22 8e-23 mol:protein length:201 S-NORCOCLAURINE SYNTHASE
blastp_pdb 3c0v_D 16 99 + 84 none 54.19 155 29.76 3e-07 mol:protein length:155 Cytokinin-specific binding protein
blastp_pdb 3c0v_C 16 99 + 84 none 54.19 155 29.76 3e-07 mol:protein length:155 Cytokinin-specific binding protein
blastp_pdb 3c0v_B 16 99 + 84 none 54.19 155 29.76 3e-07 mol:protein length:155 Cytokinin-specific binding protein
blastp_pdb 3c0v_A 16 99 + 84 none 54.19 155 29.76 3e-07 mol:protein length:155 Cytokinin-specific binding protein
blastp_pdb 2flh_D 16 99 + 84 none 54.19 155 29.76 3e-07 mol:protein length:155 cytokinin-specific binding protein
blastp_pdb 2flh_C 16 99 + 84 none 54.19 155 29.76 3e-07 mol:protein length:155 cytokinin-specific binding protein
blastp_uniprot_sprot sp|Q67A25|NCS_THLFG 4 136 + 133 Gaps:4 64.29 210 42.22 3e-22 S-norcoclaurine synthase OS Thalictrum flavum subsp. glaucum PE 1 SV 1
blastp_uniprot_sprot sp|A2A1A1|NCS2_COPJA 12 105 + 94 Gaps:1 47.45 196 41.94 3e-15 S-norcoclaurine synthase 2 OS Coptis japonica GN PR10A PE 2 SV 2
blastp_uniprot_sprot sp|P27538|PR2_PETCR 1 98 + 98 Gaps:1 61.39 158 30.93 2e-06 Pathogenesis-related protein 2 OS Petroselinum crispum GN PR2 PE 2 SV 1
rpsblast_cdd gnl|CDD|176858 16 122 + 107 none 72.30 148 25.23 1e-19 cd07816 Bet_v1-like Ligand-binding bet_v_1 domain of major pollen allergen of white birch (Betula verrucosa) Bet v 1 and related proteins. This family includes the ligand binding domain of Bet v 1 (the major pollen allergen of white birch Betula verrucosa) and related proteins. In addition to birch Bet v 1 this family includes other plant intracellular pathogenesis-related class 10 (PR-10) proteins norcoclaurine synthases (NCSs) cytokinin binding proteins (CSBPs) major latex proteins (MLPs) and ripening-related proteins. It belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. Members of this family binds a diverse range of ligands. Bet v 1 can bind brassinosteroids cytokinins flavonoids and fatty acids. Hyp-1 a PR-10 from Hypericum perforatum/St. John's wort catalyzes the condensation of two molecules of emodin to the bioactive naphthodianthrone hypericin. NCSs catalyze the condensation of dopamine and 4-hydroxyphenylacetaldehyde to (S)-norcoclaurine the first committed step in the biosynthesis of benzylisoquinoline alkaloids such as morphine. The role of MLPs is unclear however they are associated with fruit and flower development and in pathogen defense responses. A number of PR-10 proteins in this subgroup including Bet v 1 have in vitro RNase activity the biological significance of which is unclear. Bet v 1 family proteins have a conserved glycine-rich P (phosphate-binding)-loop proximal to the entrance of the ligand-binding pocket. However its conformation differs from that of the canonical P-loop structure found in nucleotide-binding proteins. Several PR-10 members including Bet v1 are allergenic. Cross-reactivity of Bet v 1 with homologs from plant foods results in birch-fruit syndrome.
rpsblast_cdd gnl|CDD|144121 16 106 + 91 Gaps:6 60.67 150 35.16 3e-07 pfam00407 Bet_v_1 Pathogenesis-related protein Bet v I family. This family is named after Bet v 1 the major birch pollen allergen. This protein belongs to family 10 of plant pathogenesis-related proteins (PR-10) cytoplasmic proteins of 15-17 kd that are wide-spread among dicotyledonous plants. In recent years a number of diverse plant proteins with low sequence similarity to Bet v 1 was identified. A classification by sequence similarity yielded several subfamilies related to PR-10: - Pathogenesis-related proteins PR-10: These proteins were identified as major tree pollen allergens in birch and related species (hazel alder) as plant food allergens expressed in high levels in fruits vegetables and seeds (apple celery hazelnut) and as pathogenesis-related proteins whose expression is induced by pathogen infection wounding or abiotic stress. Hyp-1 an enzyme involved in the synthesis of the bioactive naphthodianthrone hypericin in St. John's wort (Hypericum perforatum) also belongs to this family. Most of these proteins were found in dicotyledonous plants. In addition related sequences were identified in monocots and conifers. - Cytokinin-specific binding proteins: These legume proteins bind cytokinin plant hormones. - (S)-Norcoclaurine synthases are enzymes catalyzing the condensation of dopamine and 4-hydroxyphenylacetaldehyde to (S)-norcoclaurine the first committed step in the biosynthesis of benzylisoquinoline alkaloids such as morphine. -Major latex proteins and ripening-related proteins are proteins of unknown biological function that were first discovered in the latex of opium poppy (Papaver somniferum) and later found to be upregulated during ripening of fruits such as strawberry and cucumber. The occurrence of Bet v 1-related proteins is confined to seed plants with the exception of a cytokinin-binding protein from the moss Physcomitrella patens.

5 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 16 137 122 PTHR31213 none none none
PANTHER 16 137 122 PTHR31213:SF5 none none none
Pfam 16 129 114 PF00407 none Pathogenesis-related protein Bet v I family IPR000916
Gene3D 6 133 128 G3DSA:3.30.530.20 none none IPR023393
SUPERFAMILY 14 131 118 SSF55961 none none none

0 Localization

8 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran_2000_2002_QTL7_Delta.F Qrob_Chr09 9 v_5944_442 s_1BA1PC_866 23.51 10,96 35,74 lod 4.1466 0.041
Bourran2_2003_QTL11_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 4,16 48,16 lod 2,3 5,1
Bourran2_2004_QTL12_peak_Bud_burst_3P Qrob_Chr09 9 s_1BDO6G_250 s_1A83AM_496 34,31 9,31 44,31 lod 3,6 7,6
Bourran2_2004_QTL14_peak_Bud_burst_A4 Qrob_Chr09 9 s_1BY6BQ_440 s_1AOIKO_756 16,83 10,33 22,33 lod 3,8 9
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nSecLBD_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 35,81 34,88 37,45 lod 4.4 10.4
PM_1999_QTL15_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 9,16 47,16 lod 3,6 6,5
Bourran1_2003_QTL5_peak_Bud_burst_3P Qrob_Chr09 9 s_1ATM17_504 s_1AYZFM_899 29,81 19,81 41,81 lod 3,3 8,9

0 Targeting