Protein : Qrob_P0104180.2 Q. robur
Protein Identifier  ? Qrob_P0104180.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=5) K15040 - voltage-dependent anion channel protein 2 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 277  
Kegg Orthology  K15040
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0005741 mitochondrial outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
GO:0006820 anion transport The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0008308 voltage-gated anion channel activity Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
GO:0044070 regulation of anion transport Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

28 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cic:CICLE_v10032366mg 1 276 + 276 none 100.00 276 92.03 0.0 hypothetical protein
blastp_kegg lcl|cit:102611592 1 276 + 276 none 100.00 276 92.03 0.0 mitochondrial outer membrane protein porin of 36 kDa-like
blastp_kegg lcl|pop:POPTR_0008s19940g 1 276 + 276 none 100.00 276 91.30 0.0 POPTRDRAFT_820890 porin family protein
blastp_kegg lcl|mdm:103402924 1 276 + 276 none 100.00 276 89.13 0.0 mitochondrial outer membrane protein porin of 36 kDa
blastp_kegg lcl|pop:POPTR_0010s04240g 1 276 + 276 none 100.00 276 89.13 0.0 porin family protein
blastp_kegg lcl|rcu:RCOM_0697980 1 276 + 276 none 100.00 276 88.41 2e-179 voltage-dependent anion-selective channel putative
blastp_kegg lcl|pmum:103321627 1 276 + 276 none 100.00 276 88.04 5e-179 mitochondrial outer membrane protein porin of 36 kDa
blastp_kegg lcl|csv:101225618 1 276 + 276 none 100.00 276 89.13 2e-178 mitochondrial outer membrane protein porin of 36 kDa-like
blastp_kegg lcl|csv:101207764 1 276 + 276 none 100.00 276 89.13 2e-178 mitochondrial outer membrane protein porin of 36 kDa-like
blastp_kegg lcl|mdm:103451865 1 276 + 276 none 100.00 276 87.32 2e-178 mitochondrial outer membrane protein porin of 36 kDa-like
blastp_pdb 2k4t_A 5 275 + 271 Gaps:14 95.88 291 26.16 2e-12 mol:protein length:291 Voltage-dependent anion-selective channel pro
blastp_pdb 2jk4_A 5 275 + 271 Gaps:14 94.90 294 26.16 2e-12 mol:protein length:294 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PRO
blastp_pdb 3emn_X 5 275 + 271 Gaps:14 94.58 295 25.81 3e-12 mol:protein length:295 Voltage-dependent anion-selective channel pro
blastp_uniprot_sprot sp|P42056|VDAC2_SOLTU 1 276 + 276 none 100.00 276 85.14 4e-176 Mitochondrial outer membrane protein porin of 36 kDa OS Solanum tuberosum PE 1 SV 2
blastp_uniprot_sprot sp|P42055|VDAC1_SOLTU 1 276 + 276 none 100.00 276 76.81 3e-162 Mitochondrial outer membrane protein porin of 34 kDa OS Solanum tuberosum PE 1 SV 2
blastp_uniprot_sprot sp|Q9SRH5|VDAC1_ARATH 1 276 + 276 none 100.00 276 74.64 4e-151 Mitochondrial outer membrane protein porin 1 OS Arabidopsis thaliana GN VDAC1 PE 1 SV 3
blastp_uniprot_sprot sp|P42054|VDAC_PEA 1 276 + 276 none 100.00 276 73.55 5e-150 Outer plastidial membrane protein porin OS Pisum sativum GN POR1 PE 1 SV 2
blastp_uniprot_sprot sp|Q9SMX3|VDAC3_ARATH 1 276 + 276 Gaps:2 100.00 274 70.80 4e-143 Mitochondrial outer membrane protein porin 3 OS Arabidopsis thaliana GN VDAC3 PE 1 SV 3
blastp_uniprot_sprot sp|Q6K548|VDAC1_ORYSJ 4 276 + 273 Gaps:1 99.27 274 68.01 1e-137 Mitochondrial outer membrane protein porin 1 OS Oryza sativa subsp. japonica GN VDAC1 PE 1 SV 3
blastp_uniprot_sprot sp|P46274|VDAC1_WHEAT 4 276 + 273 Gaps:2 99.27 275 67.77 2e-133 Mitochondrial outer membrane porin OS Triticum aestivum GN VDAC1 PE 2 SV 1
blastp_uniprot_sprot sp|Q7F4F8|VDAC3_ORYSJ 4 275 + 272 Gaps:1 99.27 275 66.30 1e-128 Mitochondrial outer membrane protein porin 3 OS Oryza sativa subsp. japonica GN VDAC3 PE 2 SV 1
blastp_uniprot_sprot sp|P42057|VDAC_MAIZE 1 275 + 275 Gaps:1 99.64 277 60.51 2e-119 Outer plastidial membrane protein porin OS Zea mays GN POR1 PE 2 SV 1
blastp_uniprot_sprot sp|Q6L5I5|VDAC2_ORYSJ 7 276 + 270 Gaps:3 96.07 280 62.45 5e-115 Mitochondrial outer membrane protein porin 2 OS Oryza sativa subsp. japonica GN VDAC2 PE 2 SV 1
rpsblast_cdd gnl|CDD|201807 4 269 + 266 Gaps:10 100.00 272 45.59 2e-78 pfam01459 Porin_3 Eukaryotic porin.
rpsblast_cdd gnl|CDD|132767 5 275 + 271 Gaps:11 100.00 276 39.49 5e-74 cd07306 Porin3_VDAC Voltage-dependent anion channel of the outer mitochondrial membrane. The voltage-dependent anion channel (VDAC) regulates the flux of mostly anionic metabolites through the outer mitochondrial membrane which is highly permeable to small molecules. VDAC is the most abundant protein in the outer membrane and membrane potentials can toggle VDAC between open or high-conducting and closed or low-conducting forms. VDAC binds to and is regulated in part by hexokinase an interaction that renders mitochondria less susceptible to pro-apoptotic signals most likely by intefering with VDAC's capability to respond to Bcl-2 family proteins. While VDAC appears to play a key role in mitochondrially induced cell death a proposed involvement in forming the mitochondrial permeability transition pore which is characteristic for damaged mitochondria and apoptosis has been challenged by more recent studies.
rpsblast_cdd gnl|CDD|132766 5 274 + 270 Gaps:33 98.57 279 21.45 3e-12 cd07305 Porin3_Tom40 Translocase of outer mitochondrial membrane 40 (Tom40). Tom40 forms a channel in the mitochondrial outer membrane with a pore about 1.5 to 2.5 nanometers wide. It functions as a transport channel for unfolded protein chains and forms a complex with Tom5 Tom6 Tom7 and Tom22. The primary receptors Tom20 and Tom70 recruit the unfolded precursor protein from the mitochondrial-import stimulating factor (MSF) or cytosolic Hsc70. The precursor passes through the Tom40 channel and through another channel in the inner membrane formed by Tim23 to be finally translocated into the mitochondrial matrix. The process depends on a proton motive force across the inner membrane and requires a contact site where the outer and inner membranes come close. Tom40 is also involved in inserting outer membrane proteins into the membrane most likely not via a lateral opening in the pore but by transfering precursor proteins to an outer membrane sorting and assembly machinery.
rpsblast_cdd gnl|CDD|132765 8 270 + 263 Gaps:15 98.54 274 25.56 5e-10 cd07303 Porin3 Eukaryotic porin family that forms channels in the mitochondrial outer membrane. The porin family 3 contains two sub-families that play vital roles in the mitochondrial outer membrane a translocase for unfolded pre-proteins (Tom40) and the voltage-dependent anion channel (VDAC) that regulates the flux of mostly anionic metabolites through the outer mitochondrial membrane.
rpsblast_kog gnl|CDD|38336 2 276 + 275 Gaps:12 100.00 281 36.65 6e-69 KOG3126 KOG3126 KOG3126 Porin/voltage-dependent anion-selective channel protein [Inorganic ion transport and metabolism].

4 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 5 269 265 PF01459 none Eukaryotic porin IPR027246
PANTHER 1 276 276 PTHR11743 none none none
ProSitePatterns 219 241 23 PS00558 none Eukaryotic mitochondrial porin signature. IPR001925
Gene3D 2 275 274 G3DSA:2.40.160.10 none none IPR023614

0 Localization

0 Qtllist

0 Targeting