Protein : Qrob_P0086850.2 Q. robur

Protein Identifier  ? Qrob_P0086850.2 Organism . Name  Quercus robur
Score  3.1 Score Type  egn
Protein Description  (M=2) K10843 - DNA excision repair protein ERCC-3 [EC:3.6.4.12] Code Enzyme  EC:3.6.4.12
Gene Prediction Quality  validated Protein length 

Sequence

Length: 371  
Kegg Orthology  K10843

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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0006289 nucleotide-excision repair A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
GO:0004003 ATP-dependent DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|aly:ARALYDRAFT_916071 3 347 + 345 Gaps:107 49.02 767 74.73 0.0 DNA repair and transcription factor XPB1
blastp_kegg lcl|ath:AT5G41360 3 347 + 345 Gaps:107 49.09 766 74.47 0.0 XPB2 DNA repair helicase XPB2
blastp_kegg lcl|eus:EUTSA_v10027651mg 3 347 + 345 Gaps:107 48.89 769 73.94 2e-178 hypothetical protein
blastp_kegg lcl|mus:103973317 3 347 + 345 Gaps:107 48.58 774 73.40 1e-176 DNA repair helicase XPB1-like
blastp_kegg lcl|crb:CARUB_v10004199mg 3 347 + 345 Gaps:107 48.96 768 73.94 3e-176 hypothetical protein
blastp_kegg lcl|pda:103706419 3 347 + 345 Gaps:107 48.89 769 73.40 3e-176 DNA repair helicase XPB1
blastp_kegg lcl|sita:101779540 3 347 + 345 Gaps:107 49.15 765 73.14 7e-175 DNA repair helicase XPB1-like
blastp_kegg lcl|bdi:100822542 3 347 + 345 Gaps:107 49.09 766 73.14 1e-174 DNA repair helicase XPB2-like
blastp_kegg lcl|ath:AT5G41370 3 347 + 345 Gaps:107 49.02 767 75.53 8e-174 XPB1 DNA repair helicase XPB1
blastp_kegg lcl|brp:103864077 3 367 + 365 Gaps:107 51.63 767 72.22 1e-173 DNA repair helicase XPB1
blastp_pdb 2fwr_D 3 336 + 334 Gaps:93 75.64 472 26.89 6e-13 mol:protein length:472 DNA repair protein RAD25
blastp_pdb 2fwr_C 3 336 + 334 Gaps:93 75.64 472 26.89 6e-13 mol:protein length:472 DNA repair protein RAD25
blastp_pdb 2fwr_B 3 336 + 334 Gaps:93 75.64 472 26.89 6e-13 mol:protein length:472 DNA repair protein RAD25
blastp_pdb 2fwr_A 3 336 + 334 Gaps:93 75.64 472 26.89 6e-13 mol:protein length:472 DNA repair protein RAD25
blastp_pdb 2fzl_A 208 331 + 124 Gaps:30 53.88 219 44.07 2e-10 mol:protein length:219 DNA repair protein RAD25 XPB
blastp_uniprot_sprot sp|Q9FUG4|XPB2_ARATH 3 347 + 345 Gaps:107 49.09 766 74.47 0.0 DNA repair helicase XPB2 OS Arabidopsis thaliana GN XPB2 PE 2 SV 1
blastp_uniprot_sprot sp|Q38861|XPB1_ARATH 3 347 + 345 Gaps:107 49.02 767 75.53 3e-175 DNA repair helicase XPB1 OS Arabidopsis thaliana GN XPB1 PE 2 SV 3
blastp_uniprot_sprot sp|O00835|ERCC3_DICDI 3 347 + 345 Gaps:115 46.00 800 55.43 1e-112 TFIIH basal transcription factor complex helicase repB subunit OS Dictyostelium discoideum GN repB PE 2 SV 1
blastp_uniprot_sprot sp|Q5ZKK7|ERCC3_CHICK 3 347 + 345 Gaps:116 46.57 788 51.50 3e-106 TFIIH basal transcription factor complex helicase XPB subunit OS Gallus gallus GN ERCC3 PE 2 SV 1
blastp_uniprot_sprot sp|P19447|ERCC3_HUMAN 3 347 + 345 Gaps:116 46.93 782 51.50 2e-105 TFIIH basal transcription factor complex helicase XPB subunit OS Homo sapiens GN ERCC3 PE 1 SV 1
blastp_uniprot_sprot sp|Q60HG1|ERCC3_MACFA 3 347 + 345 Gaps:116 46.93 782 51.50 2e-105 TFIIH basal transcription factor complex helicase XPB subunit OS Macaca fascicularis GN ERCC3 PE 2 SV 1
blastp_uniprot_sprot sp|Q5RA62|ERCC3_PONAB 3 347 + 345 Gaps:116 46.93 782 51.50 2e-105 TFIIH basal transcription factor complex helicase XPB subunit OS Pongo abelii GN ERCC3 PE 2 SV 1
blastp_uniprot_sprot sp|P49135|ERCC3_MOUSE 3 347 + 345 Gaps:116 46.87 783 51.50 2e-105 TFIIH basal transcription factor complex helicase XPB subunit OS Mus musculus GN Ercc3 PE 2 SV 1
blastp_uniprot_sprot sp|Q1RMT1|ERCC3_BOVIN 3 347 + 345 Gaps:116 46.93 782 51.23 4e-105 TFIIH basal transcription factor complex helicase XPB subunit OS Bos taurus GN ERCC3 PE 2 SV 1
blastp_uniprot_sprot sp|Q4G005|ERCC3_RAT 3 347 + 345 Gaps:116 46.93 782 51.23 4e-105 TFIIH basal transcription factor complex helicase XPB subunit OS Rattus norvegicus GN Ercc3 PE 2 SV 1
rpsblast_cdd gnl|CDD|161952 12 347 + 336 Gaps:115 49.04 732 59.89 1e-145 TIGR00603 rad25 DNA repair helicase rad25. All proteins in this family for which functions are known are DNA-DNA helicases used for the initiation of nucleotide excision repair and transacription as part of the TFIIH complex.This family is based on the phylogenomic analysis of JA Eisen (1999 Ph.D. Thesis Stanford University).
rpsblast_cdd gnl|CDD|31261 10 349 + 340 Gaps:120 83.26 442 27.72 1e-37 COG1061 SSL2 DNA or RNA helicases of superfamily II [Transcription / DNA replication recombination and repair].
rpsblast_cdd gnl|CDD|201125 250 308 + 59 Gaps:9 84.62 78 30.30 1e-08 pfam00271 Helicase_C Helicase conserved C-terminal domain. The Prosite family is restricted to DEAD/H helicases whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit but an integral part of the helicase.
rpsblast_cdd gnl|CDD|28960 202 307 + 106 Gaps:15 89.31 131 26.50 3e-07 cd00079 HELICc Helicase superfamily c-terminal domain associated with DEXDc- DEAD- and DEAH-box proteins yeast initiation factor 4A Ski2p and Hepatitis C virus NS3 helicases this domain is found in a wide variety of helicases and helicase related proteins may not be an autonomously folding unit but an integral part of the helicase 4 helicase superfamilies at present according to the organization of their signature motifs all helicases share the ability to unwind nucleic acid duplexes with a distinct directional polarity they utilize the free energy from nucleoside triphosphate hydrolysis to fuel their translocation along DNA unwinding the duplex in the process.
rpsblast_cdd gnl|CDD|197757 250 308 + 59 Gaps:9 80.49 82 27.27 4e-07 smart00490 HELICc helicase superfamily c-terminal domain.

16 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 203 308 106 G3DSA:3.40.50.300 none none IPR027417
SMART 239 308 70 SM00490 none helicase superfamily c-terminal domain IPR001650
SUPERFAMILY 200 337 138 SSF52540 none none IPR027417
Gene3D 13 131 119 G3DSA:3.40.50.300 none none IPR027417
SUPERFAMILY 13 131 119 SSF52540 none none IPR027417
ProSiteProfiles 7 165 159 PS51192 none Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. IPR014001
PRINTS 264 282 19 PR00851 none Xeroderma pigmentosum group B protein signature IPR001161
PRINTS 320 343 24 PR00851 none Xeroderma pigmentosum group B protein signature IPR001161
PRINTS 8 30 23 PR00851 none Xeroderma pigmentosum group B protein signature IPR001161
PRINTS 283 308 26 PR00851 none Xeroderma pigmentosum group B protein signature IPR001161
PANTHER 4 162 159 PTHR11274 none none none
PANTHER 195 347 153 PTHR11274 none none none
PANTHER 4 162 159 PTHR11274:SF0 none none none
PANTHER 195 347 153 PTHR11274:SF0 none none none
ProSiteProfiles 211 353 143 PS51194 none Superfamilies 1 and 2 helicase C-terminal domain profile. IPR001650
Pfam 249 308 60 PF00271 none Helicase conserved C-terminal domain IPR001650

0 Localization

12 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
Bourran2_2004_QTL9_peak_Bud_burst_3P Qrob_Chr02 2 s_1C34E9_788 v_12238_322 50 25 75 lod 4,4 10,1
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL2_d13Cf Qrob_Chr02 2 s_1AQA4Z_1644 s_1AK5QX_947 53.67 14,01 79,68 lod 5.6594 0.03
Bourran1_2004_QTL2_peak_Bud_burst_3P Qrob_Chr02 2 s_1AW12F_382 s_1A77MR_223 42 6 64 lod 3,6 9,6
Bourran_2000_2002_QTL2_Delta.F Qrob_Chr02 2 s_1CSO13_1244 s_1AVEUF_1540 55.44 46,71 63,68 lod 7.3232 0.058
Bourran2_2002_QTL7_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 29 52 lod 8,1 16
Bourran2_2002_QTL9_peak_Bud_burst_A4 Qrob_Chr02 2 s_1BFNDA_375 s_1A3VA1_2139 32,5 17 62 lod 3,1 4,2
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nP_A4 Qrob_Chr02 2 s_1A0FUE_1868 s_1A1UAI_500 20,64 20,47 21,36 lod 5.8 10.9
Bourran2_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 24,87 24,63 26,18 lod 3.8 7
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL6_d13Cf Qrob_Chr02 2 s_1AEP21_172 v_6048_204 46.33 22,5 65,23 lod 4.972 0.03

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 72   Mitochondrion 4 0.037 0.657 NON-PLANT 72