Protein : Qrob_P0080150.2 Q. robur
Protein Identifier  ? Qrob_P0080150.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) PTHR13994:SF5 - GB DEF: FIBROBLAST GROWTH FACTOR PUTATIVE ISOFORM 2 Code Enzyme  EC:3.6.1.22, EC:3.6.1.13
Gene Prediction Quality  validated Protein length 

Sequence

Length: 366  
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0 Synonyms

1 GO Terms

Identifier Name Description
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

40 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|fve:101294664 1 362 + 362 Gaps:7 98.40 375 71.00 0.0 nudix hydrolase 8-like
blastp_kegg lcl|pper:PRUPE_ppa007315mg 1 364 + 364 Gaps:10 99.73 373 71.77 0.0 hypothetical protein
blastp_kegg lcl|pxb:103926619 1 362 + 362 Gaps:11 99.20 376 72.65 0.0 nudix hydrolase 8
blastp_kegg lcl|pmum:103337046 1 364 + 364 Gaps:14 99.73 377 71.54 0.0 nudix hydrolase 8
blastp_kegg lcl|rcu:RCOM_0006430 1 362 + 362 Gaps:5 99.18 368 69.59 0.0 mutt domain protein putative (EC:3.6.1.22)
blastp_kegg lcl|tcc:TCM_015906 1 362 + 362 Gaps:6 99.18 365 69.34 0.0 Nudix hydrolase
blastp_kegg lcl|gmx:100815507 1 362 + 362 Gaps:6 99.18 367 70.05 0.0 nudix hydrolase 8-like
blastp_kegg lcl|pop:POPTR_0001s15410g 2 362 + 361 Gaps:6 98.66 372 66.49 3e-178 hypothetical protein
blastp_kegg lcl|mtr:MTR_4g100480 1 362 + 362 Gaps:8 99.16 357 67.23 4e-173 Nudix hydrolase
blastp_kegg lcl|cam:101493680 1 362 + 362 Gaps:8 99.18 365 66.57 2e-171 nudix hydrolase 8-like
blastp_pdb 3h95_A 191 306 + 116 Gaps:6 58.29 199 42.24 1e-17 mol:protein length:199 Nucleoside diphosphate-linked moiety X motif
blastp_pdb 3fxt_H 105 183 + 79 Gaps:4 73.45 113 37.35 5e-12 mol:protein length:113 Nucleoside diphosphate-linked moiety X motif
blastp_pdb 3fxt_G 105 183 + 79 Gaps:4 73.45 113 37.35 5e-12 mol:protein length:113 Nucleoside diphosphate-linked moiety X motif
blastp_pdb 3fxt_F 105 183 + 79 Gaps:4 73.45 113 37.35 5e-12 mol:protein length:113 Nucleoside diphosphate-linked moiety X motif
blastp_pdb 3fxt_E 105 183 + 79 Gaps:4 73.45 113 37.35 5e-12 mol:protein length:113 Nucleoside diphosphate-linked moiety X motif
blastp_pdb 3fxt_D 105 183 + 79 Gaps:4 73.45 113 37.35 5e-12 mol:protein length:113 Nucleoside diphosphate-linked moiety X motif
blastp_pdb 3fxt_C 105 183 + 79 Gaps:4 73.45 113 37.35 5e-12 mol:protein length:113 Nucleoside diphosphate-linked moiety X motif
blastp_pdb 3fxt_B 105 183 + 79 Gaps:4 73.45 113 37.35 5e-12 mol:protein length:113 Nucleoside diphosphate-linked moiety X motif
blastp_pdb 3fxt_A 105 183 + 79 Gaps:4 73.45 113 37.35 5e-12 mol:protein length:113 Nucleoside diphosphate-linked moiety X motif
blastp_uniprot_sprot sp|Q8L7W2|NUDT8_ARATH 10 358 + 349 Gaps:28 95.66 369 64.02 2e-149 Nudix hydrolase 8 OS Arabidopsis thaliana GN NUDT8 PE 2 SV 2
blastp_uniprot_sprot sp|Q94B74|NUDT2_ARATH 99 354 + 256 Gaps:3 91.01 278 49.41 1e-80 Nudix hydrolase 2 OS Arabidopsis thaliana GN NUDT2 PE 1 SV 1
blastp_uniprot_sprot sp|Q6NPD7|NUD10_ARATH 86 359 + 274 Gaps:10 95.31 277 50.00 2e-80 Nudix hydrolase 10 OS Arabidopsis thaliana GN NUDT10 PE 1 SV 1
blastp_uniprot_sprot sp|Q9SJC4|NUDT6_ARATH 99 354 + 256 Gaps:5 90.81 283 48.64 1e-69 Nudix hydrolase 6 OS Arabidopsis thaliana GN NUDT6 PE 1 SV 1
blastp_uniprot_sprot sp|Q9SJC6|NUDT5_ARATH 93 334 + 242 Gaps:10 83.44 302 45.63 1e-69 Nudix hydrolase 5 OS Arabidopsis thaliana GN NUDT5 PE 2 SV 3
blastp_uniprot_sprot sp|Q9SU14|NUDT7_ARATH 99 353 + 255 Gaps:4 90.43 282 45.88 6e-68 Nudix hydrolase 7 OS Arabidopsis thaliana GN NUDT7 PE 1 SV 1
blastp_uniprot_sprot sp|P53370|NUDT6_HUMAN 105 306 + 202 Gaps:10 65.19 316 40.29 2e-38 Nucleoside diphosphate-linked moiety X motif 6 OS Homo sapiens GN NUDT6 PE 1 SV 2
blastp_uniprot_sprot sp|P13420|NUDT6_XENLA 151 352 + 202 Gaps:20 93.09 217 42.08 8e-38 Nucleoside diphosphate-linked moiety X motif 6 OS Xenopus laevis GN nudt6 PE 1 SV 1
blastp_uniprot_sprot sp|P70563|NUDT6_RAT 105 301 + 197 Gaps:10 64.22 313 37.31 4e-33 Nucleoside diphosphate-linked moiety X motif 6 OS Rattus norvegicus GN Nudt6 PE 1 SV 1
blastp_uniprot_sprot sp|Q8CH40|NUDT6_MOUSE 105 306 + 202 Gaps:10 65.81 313 35.44 7e-32 Nucleoside diphosphate-linked moiety X motif 6 OS Mus musculus GN Nudt6 PE 2 SV 1
rpsblast_cdd gnl|CDD|72906 192 323 + 132 Gaps:5 100.00 127 60.63 5e-48 cd04670 Nudix_Hydrolase_12 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties X. Enzymes belonging to this superfamily require a divalent cation such as Mg2+ or Mn2+ for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU where U I L or V) which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates dinucleoside polyphosphates nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically substrate hydrolysis occurs by a nucleophilic substitution reaction with variation in the numbers and roles of divalent cations required..

12 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
ProSiteProfiles 191 321 131 PS51462 none Nudix hydrolase domain profile. IPR000086
Gene3D 187 315 129 G3DSA:3.90.79.10 none none IPR015797
PRINTS 189 207 19 PR01356 none Anti-sense to fibroblast growth factor protein GFG signature IPR003293
PRINTS 329 353 25 PR01356 none Anti-sense to fibroblast growth factor protein GFG signature IPR003293
PRINTS 277 301 25 PR01356 none Anti-sense to fibroblast growth factor protein GFG signature IPR003293
PRINTS 173 189 17 PR01356 none Anti-sense to fibroblast growth factor protein GFG signature IPR003293
PRINTS 151 169 19 PR01356 none Anti-sense to fibroblast growth factor protein GFG signature IPR003293
ProSitePatterns 228 249 22 PS00893 none Nudix box signature. IPR020084
PANTHER 97 354 258 PTHR13994:SF5 none none none
Pfam 193 308 116 PF00293 none NUDIX domain IPR000086
PANTHER 97 354 258 PTHR13994 none none none
SUPERFAMILY 159 323 165 SSF55811 none none IPR015797

0 Localization

5 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7
Bourran2_2015_nSecLBD_3P Qrob_Chr12 12 s_A4YYC_633 s_2F1IZB_703 18,64 18,01 21,53 lod 6.5 17.2
Bourran2_2002_QTL17_peak_Bud_burst_A4 Qrob_Chr12 12 s_1CTJ3J_556 s_1CTJ3J_556 0 0 25 lod 2,9 6
Bourran2_2014_nSeqBC_3P Qrob_Chr12 12 s_1EO8V5_710 s_1A2VMU_355 11,04 0 32,58 lod 1,7196 4,7

0 Targeting