Protein : Qrob_P0072900.2 Q. robur

Protein Identifier  ? Qrob_P0072900.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) PF00609//PF00781 - Diacylglycerol kinase accessory domain // Diacylglycerol kinase catalytic domain Code Enzyme  EC:2.7.1.107
Gene Prediction Quality  validated Protein length 

Sequence

Length: 531  
Kegg Orthology  K00901

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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0016301 kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0004143 diacylglycerol kinase activity Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.
GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).

27 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_1255930 28 530 + 503 Gaps:11 97.72 526 77.82 0.0 diacylglycerol kinase alpha putative (EC:2.7.1.107)
blastp_kegg lcl|pda:103717315 54 530 + 477 Gaps:3 97.76 491 80.21 0.0 diacylglycerol kinase 5-like
blastp_kegg lcl|tcc:TCM_031295 1 530 + 530 Gaps:8 100.00 528 76.70 0.0 Diacylglycerol kinase 5
blastp_kegg lcl|gmx:100801004 36 530 + 495 Gaps:1 98.02 504 79.35 0.0 diacylglycerol kinase 5-like
blastp_kegg lcl|pvu:PHAVU_011G155800g 40 530 + 491 Gaps:2 97.60 501 78.73 0.0 hypothetical protein
blastp_kegg lcl|mus:103986345 51 530 + 480 Gaps:4 89.93 536 78.22 0.0 diacylglycerol kinase 5-like isoform X1
blastp_kegg lcl|mus:103972452 54 530 + 477 Gaps:1 99.17 482 76.78 0.0 diacylglycerol kinase 5-like
blastp_kegg lcl|pda:103709886 45 520 + 476 Gaps:5 97.76 492 77.13 0.0 diacylglycerol kinase 5-like
blastp_kegg lcl|pper:PRUPE_ppa021564mg 44 530 + 487 Gaps:3 100.00 490 78.16 0.0 hypothetical protein
blastp_kegg lcl|cic:CICLE_v10015037mg 53 530 + 478 Gaps:1 97.96 489 77.04 0.0 hypothetical protein
blastp_uniprot_sprot sp|Q9C5E5|DGK5_ARATH 54 523 + 470 Gaps:10 93.12 509 75.32 0.0 Diacylglycerol kinase 5 OS Arabidopsis thaliana GN DGK5 PE 2 SV 1
blastp_uniprot_sprot sp|F4JKI3|DGK6_ARATH 54 499 + 446 Gaps:10 94.85 466 71.04 0.0 Diacylglycerol kinase 6 OS Arabidopsis thaliana GN DGK6 PE 3 SV 1
blastp_uniprot_sprot sp|F4JQ95|DGK7_ARATH 59 460 + 402 Gaps:9 81.91 492 36.72 2e-81 Diacylglycerol kinase 7 OS Arabidopsis thaliana GN DGK7 PE 1 SV 1
blastp_uniprot_sprot sp|Q8VZG1|DGK3_ARATH 59 472 + 414 Gaps:21 84.63 488 37.29 3e-81 Diacylglycerol kinase 3 OS Arabidopsis thaliana GN DGK3 PE 2 SV 1
blastp_uniprot_sprot sp|Q1PDI2|DGK4_ARATH 70 460 + 391 Gaps:18 80.70 487 36.39 2e-77 Diacylglycerol kinase 4 OS Arabidopsis thaliana GN DGK4 PE 2 SV 1
blastp_uniprot_sprot sp|P34125|DGKA_DICDI 74 473 + 400 Gaps:68 39.68 887 35.23 9e-41 Diacylglycerol kinase A OS Dictyostelium discoideum GN dgkA PE 1 SV 3
blastp_uniprot_sprot sp|Q03603|DGK3_CAEEL 61 483 + 423 Gaps:90 47.42 795 32.89 2e-39 Probable diacylglycerol kinase 3 OS Caenorhabditis elegans GN dgk-3 PE 3 SV 3
blastp_uniprot_sprot sp|O75912|DGKI_HUMAN 80 487 + 408 Gaps:72 32.30 1065 36.63 3e-39 Diacylglycerol kinase iota OS Homo sapiens GN DGKI PE 1 SV 1
blastp_uniprot_sprot sp|Q80UP3|DGKZ_MOUSE 80 449 + 370 Gaps:75 33.48 929 36.98 1e-38 Diacylglycerol kinase zeta OS Mus musculus GN Dgkz PE 1 SV 2
blastp_uniprot_sprot sp|O08560|DGKZ_RAT 80 449 + 370 Gaps:75 33.48 929 36.98 1e-38 Diacylglycerol kinase zeta OS Rattus norvegicus GN Dgkz PE 1 SV 1
rpsblast_cdd gnl|CDD|201338 273 447 + 175 Gaps:21 99.36 157 38.46 4e-39 pfam00609 DAGK_acc Diacylglycerol kinase accessory domain. Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. This domain is assumed to be an accessory domain: its function is unknown.
rpsblast_cdd gnl|CDD|128360 275 447 + 173 Gaps:18 98.12 160 36.31 3e-27 smart00045 DAGKa Diacylglycerol kinase accessory domain (presumed). Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. DAG can be produced from the hydrolysis of phosphatidylinositol 4 5-bisphosphate (PIP2) by a phosphoinositide-specific phospholipase C and by the degradation of phosphatidylcholine (PC) by a phospholipase C or the concerted actions of phospholipase D and phosphatidate phosphohydrolase. This domain might either be an accessory domain or else contribute to the catalytic domain. Bacterial homologues are known.
rpsblast_cdd gnl|CDD|201440 80 201 + 122 Gaps:16 86.61 127 31.82 3e-18 pfam00781 DAGK_cat Diacylglycerol kinase catalytic domain. Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologues. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs revealing a novel metal-binding site. The residues of this site are conserved across the family.
rpsblast_cdd gnl|CDD|197486 82 196 + 115 Gaps:16 81.45 124 46.53 5e-17 smart00046 DAGKc Diacylglycerol kinase catalytic domain (presumed). Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. DAG can be produced from the hydrolysis of phosphatidylinositol 4 5-bisphosphate (PIP2) by a phosphoinositide-specific phospholipase C and by the degradation of phosphatidylcholine (PC) by a phospholipase C or the concerted actions of phospholipase D and phosphatidate phosphohydrolase. This domain is presumed to be the catalytic domain. Bacterial homologues areknown.
rpsblast_kog gnl|CDD|36384 34 488 + 455 Gaps:60 63.88 634 34.07 1e-100 KOG1169 KOG1169 KOG1169 Diacylglycerol kinase [Lipid transport and metabolism Signal transduction mechanisms].
rpsblast_kog gnl|CDD|36001 70 449 + 380 Gaps:75 31.97 1004 36.45 5e-43 KOG0782 KOG0782 KOG0782 Predicted diacylglycerol kinase [Signal transduction mechanisms].
rpsblast_kog gnl|CDD|36385 71 511 + 441 Gaps:63 30.21 1099 34.34 9e-19 KOG1170 KOG1170 KOG1170 Diacylglycerol kinase [Lipid transport and metabolism].

12 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 81 202 122 PF00781 none Diacylglycerol kinase catalytic domain IPR001206
ProSiteProfiles 76 229 154 PS50146 none DAG-kinase catalytic (DAGKc) domain profile. IPR001206
PANTHER 136 528 393 PTHR11255 none none none
PANTHER 51 120 70 PTHR11255 none none none
SMART 275 447 173 SM00045 "KEGG:00561+2.7.1.107","KEGG:00564+2.7.1.107","MetaCyc:PWY-7039","Reactome:REACT_14797","Reactome:REACT_604" Diacylglycerol kinase accessory domain (presumed) IPR000756
Pfam 273 447 175 PF00609 "KEGG:00561+2.7.1.107","KEGG:00564+2.7.1.107","MetaCyc:PWY-7039","Reactome:REACT_14797","Reactome:REACT_604" Diacylglycerol kinase accessory domain IPR000756
PANTHER 136 528 393 PTHR11255:SF29 none none none
PANTHER 51 120 70 PTHR11255:SF29 none none none
SMART 80 223 144 SM00046 none Diacylglycerol kinase catalytic domain (presumed) IPR001206
SUPERFAMILY 264 454 191 SSF111331 none none IPR016064
SUPERFAMILY 79 225 147 SSF111331 none none IPR016064
Coils 489 510 22 Coil none none none

0 Localization

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_rEpiBC_3P Qrob_Chr05 5 s_2GDU0O_517 s_1BT8O3_239 25,81 0 55,45 lod 2,2101 5,5

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 103   Mitochondrion 2 0.051 0.816 NON-PLANT 103