Protein : Qrob_P0071270.2 Q. robur

Protein Identifier  ? Qrob_P0071270.2 Organism . Name  Quercus robur
Score  97.0 Score Type  egn
Protein Description  (M=3) K13941 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15] Gene Prediction Quality  validated
Protein length 

Sequence

Length: 514  
Kegg Orthology  K13941

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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0009396 folic acid-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.
GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+).
GO:0004156 dihydropteroate synthase activity Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate.
GO:0042558 pteridine-containing compound metabolic process The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa004379mg 1 509 + 509 none 99.22 513 78.19 0.0 hypothetical protein
blastp_kegg lcl|pmum:103319098 1 509 + 509 none 99.22 513 78.19 0.0 folic acid synthesis protein fol1-like
blastp_kegg lcl|tcc:TCM_011500 1 511 + 511 none 100.00 511 78.28 0.0 Dihydropterin pyrophosphokinase / Dihydropteroate synthase
blastp_kegg lcl|pxb:103941646 1 509 + 509 none 98.64 516 78.19 0.0 folic acid synthesis protein fol1-like
blastp_kegg lcl|pxb:103941643 1 509 + 509 none 98.64 516 78.19 0.0 folic acid synthesis protein fol1-like
blastp_kegg lcl|fve:101295774 1 507 + 507 none 98.07 517 77.32 0.0 folic acid synthesis protein fol1-like
blastp_kegg lcl|mdm:103446277 1 509 + 509 none 98.64 516 77.80 0.0 folic acid synthesis protein fol1-like
blastp_kegg lcl|cic:CICLE_v10031260mg 1 506 + 506 none 98.44 514 75.89 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0008s09700g 1 509 + 509 none 99.61 511 76.23 0.0 POPTRDRAFT_419321 hypothetical protein
blastp_kegg lcl|pvu:PHAVU_007G262100g 1 509 + 509 Gaps:1 98.83 514 75.20 0.0 hypothetical protein
blastp_pdb 2bmb_A 44 505 + 462 Gaps:74 96.15 545 32.63 1e-72 mol:protein length:545 FOLIC ACID SYNTHESIS PROTEIN FOL1
blastp_pdb 4db7_B 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_pdb 4db7_A 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_pdb 4dai_B 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_pdb 4dai_A 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_pdb 4daf_B 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_pdb 4daf_A 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_pdb 4d9p_B 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_pdb 4d9p_A 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_pdb 4d8z_B 225 504 + 280 Gaps:24 86.87 297 42.25 5e-56 mol:protein length:297 Dihydropteroate Synthase
blastp_uniprot_sprot sp|P29251|FOL1_PNECA 24 506 + 483 Gaps:37 62.97 740 42.06 6e-95 Folic acid synthesis protein fol1 OS Pneumocystis carinii GN fol1 PE 1 SV 1
blastp_uniprot_sprot sp|Q4LB35|FOL1_SCHPO 48 503 + 456 Gaps:32 58.66 733 41.16 3e-84 Folic acid synthesis protein fol1 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN fol1 PE 1 SV 2
blastp_uniprot_sprot sp|P53848|FOL1_YEAST 29 505 + 477 Gaps:74 65.41 824 32.65 3e-72 Folic acid synthesis protein FOL1 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN FOL1 PE 1 SV 2
blastp_uniprot_sprot sp|P73248|DHPS_SYNY3 217 505 + 289 Gaps:14 95.16 289 44.36 1e-65 Dihydropteroate synthase OS Synechocystis sp. (strain PCC 6803 / Kazusa) GN folP PE 3 SV 1
blastp_uniprot_sprot sp|Q54YD9|FOL1_DICDI 46 505 + 460 Gaps:40 65.30 657 38.46 7e-64 Folic acid synthesis protein FOL1 OS Dictyostelium discoideum GN fol1 PE 3 SV 1
blastp_uniprot_sprot sp|P0AC15|DHPS_SHIFL 232 510 + 279 Gaps:16 93.26 282 41.44 9e-55 Dihydropteroate synthase OS Shigella flexneri GN folP PE 3 SV 1
blastp_uniprot_sprot sp|P0AC13|DHPS_ECOLI 232 510 + 279 Gaps:16 93.26 282 41.44 9e-55 Dihydropteroate synthase OS Escherichia coli (strain K12) GN folP PE 1 SV 1
blastp_uniprot_sprot sp|P0AC14|DHPS_ECOL6 232 510 + 279 Gaps:16 93.26 282 41.44 9e-55 Dihydropteroate synthase OS Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN folP PE 3 SV 1
blastp_uniprot_sprot sp|P28822|DHPS_BACSU 215 506 + 292 Gaps:28 94.74 285 42.22 4e-53 Dihydropteroate synthase OS Bacillus subtilis (strain 168) GN sul PE 3 SV 2
blastp_uniprot_sprot sp|O05701|DHPS_STAAU 229 511 + 283 Gaps:29 98.13 267 41.60 4e-53 Dihydropteroate synthase OS Staphylococcus aureus GN folP PE 1 SV 1

14 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 47 172 126 PF01288 "KEGG:00790+2.7.6.3","MetaCyc:PWY-6147","MetaCyc:PWY-6148","MetaCyc:PWY-6797","MetaCyc:PWY-7539","UniPathway:UPA00077" 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) IPR000550
TIGRFAM 232 503 272 TIGR01496 "KEGG:00790+2.5.1.15","MetaCyc:PWY-6614","UniPathway:UPA00077" DHPS: dihydropteroate synthase IPR006390
PANTHER 31 509 479 PTHR20941:SF1 none none none
Gene3D 229 505 277 G3DSA:3.20.20.20 none none IPR000489
Pfam 235 455 221 PF00809 none Pterin binding enzyme IPR000489
ProSitePatterns 129 140 12 PS00794 "KEGG:00790+2.7.6.3","MetaCyc:PWY-6147","MetaCyc:PWY-6148","MetaCyc:PWY-6797","MetaCyc:PWY-7539","UniPathway:UPA00077" 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. IPR000550
ProSiteProfiles 230 498 269 PS50972 none Pterin-binding domain profile. IPR000489
SUPERFAMILY 220 505 286 SSF51717 none none IPR011005
SUPERFAMILY 46 174 129 SSF55083 "KEGG:00790+2.7.6.3","MetaCyc:PWY-6147","MetaCyc:PWY-6148","MetaCyc:PWY-6797","MetaCyc:PWY-7539","UniPathway:UPA00077" none IPR000550
Gene3D 45 173 129 G3DSA:3.30.70.560 "KEGG:00790+2.7.6.3","MetaCyc:PWY-6147","MetaCyc:PWY-6148","MetaCyc:PWY-6797","MetaCyc:PWY-7539","UniPathway:UPA00077" none IPR000550
TIGRFAM 46 172 127 TIGR01498 "KEGG:00790+2.7.6.3","MetaCyc:PWY-6147","MetaCyc:PWY-6148","MetaCyc:PWY-6797","MetaCyc:PWY-7539","UniPathway:UPA00077" folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase IPR000550
ProSitePatterns 232 247 16 PS00792 none Dihydropteroate synthase signature 1. IPR000489
ProSitePatterns 266 279 14 PS00793 none Dihydropteroate synthase signature 2. IPR000489
PANTHER 31 509 479 PTHR20941 none none none

0 Localization

0 Qtllist

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 31   Mitochondrion 2 0.025 0.911 NON-PLANT 31