Protein : Qrob_P0070830.2 Q. robur
Protein Identifier  ? Qrob_P0070830.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K00655 - 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] Code Enzyme  EC:2.3.1.51
Gene Prediction Quality  validated Protein length 

Sequence

Length: 327  
Kegg Orthology  K00655
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0016746 transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.
GO:0008654 phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_037041 12 326 + 315 none 87.74 359 74.60 4e-168 Phospholipid/glycerol acyltransferase family protein isoform 1
blastp_kegg lcl|vvi:100248458 3 326 + 324 none 87.80 369 72.53 6e-168 1-acyl-sn-glycerol-3-phosphate acyltransferase 1 chloroplastic-like
blastp_kegg lcl|rcu:RCOM_0623360 21 326 + 306 Gaps:5 99.34 303 74.42 9e-159 1-acyl-sn-glycerol-3-phosphate acyltransferase putative (EC:2.3.1.51)
blastp_kegg lcl|cit:102610157 8 326 + 319 Gaps:8 89.37 348 72.67 8e-158 1-acyl-sn-glycerol-3-phosphate acyltransferase 1 chloroplastic-like
blastp_kegg lcl|pop:POPTR_0006s19730g 8 326 + 319 Gaps:8 86.23 363 73.48 2e-156 POPTRDRAFT_762928 hypothetical protein
blastp_kegg lcl|csv:101225925 11 326 + 316 Gaps:4 95.12 328 70.19 5e-153 1-acyl-sn-glycerol-3-phosphate acyltransferase 1 chloroplastic-like
blastp_kegg lcl|pper:PRUPE_ppa015179mg 3 326 + 324 none 97.59 332 67.90 8e-153 hypothetical protein
blastp_kegg lcl|mdm:103456379 3 326 + 324 Gaps:2 90.70 355 68.32 2e-152 1-acyl-sn-glycerol-3-phosphate acyltransferase 1 chloroplastic-like
blastp_kegg lcl|mdm:103431374 3 326 + 324 Gaps:2 90.70 355 68.32 4e-152 1-acyl-sn-glycerol-3-phosphate acyltransferase 1 chloroplastic-like
blastp_kegg lcl|pmum:103341273 3 326 + 324 none 90.76 357 67.90 5e-152 1-acyl-sn-glycerol-3-phosphate acyltransferase 1 chloroplastic
blastp_uniprot_sprot sp|Q9LLY4|LPAT1_BRANA 8 324 + 317 Gaps:12 88.66 344 62.62 1e-131 1-acyl-sn-glycerol-3-phosphate acyltransferase 1 chloroplastic OS Brassica napus GN LPAT1 PE 2 SV 1
blastp_uniprot_sprot sp|Q8GXU8|LPAT1_ARATH 36 324 + 289 Gaps:1 80.90 356 64.24 5e-131 1-acyl-sn-glycerol-3-phosphate acyltransferase 1 chloroplastic OS Arabidopsis thaliana GN LPAT1 PE 1 SV 1
blastp_uniprot_sprot sp|P33333|PLSC_YEAST 148 323 + 176 Gaps:18 60.07 303 35.16 6e-19 Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN SLC1 PE 1 SV 1
blastp_uniprot_sprot sp|Q42670|PLSC_COCNU 92 278 + 187 Gaps:8 59.42 308 31.69 1e-16 1-acyl-sn-glycerol-3-phosphate acyltransferase OS Cocos nucifera PE 1 SV 1
blastp_uniprot_sprot sp|Q42870|PLSC_LIMDO 97 278 + 182 Gaps:9 62.99 281 31.64 2e-16 1-acyl-sn-glycerol-3-phosphate acyltransferase OS Limnanthes douglasii GN PLSC PE 2 SV 1
blastp_uniprot_sprot sp|Q42868|PLSC_LIMAL 97 278 + 182 Gaps:9 62.99 281 31.64 1e-15 1-acyl-sn-glycerol-3-phosphate acyltransferase OS Limnanthes alba PE 2 SV 1
blastp_uniprot_sprot sp|Q99943|PLCA_HUMAN 148 325 + 178 Gaps:13 61.84 283 32.00 1e-15 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha OS Homo sapiens GN AGPAT1 PE 1 SV 2
blastp_uniprot_sprot sp|Q95JH2|PLCA_BOVIN 148 325 + 178 Gaps:13 60.98 287 32.00 2e-15 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha OS Bos taurus GN AGPAT1 PE 2 SV 1
blastp_uniprot_sprot sp|O35083|PLCA_MOUSE 148 325 + 178 Gaps:10 61.75 285 28.98 1e-14 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha OS Mus musculus GN Agpat1 PE 2 SV 1
blastp_uniprot_sprot sp|Q9US20|YLD2_SCHPO 131 318 + 188 Gaps:9 69.18 279 32.12 1e-14 Uncharacterized acyltransferase C1851.02 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN SPAC1851.02 PE 3 SV 1
rpsblast_cdd gnl|CDD|178489 114 326 + 213 none 99.53 214 80.28 1e-117 PLN02901 PLN02901 1-acyl-sn-glycerol-3-phosphate acyltransferase.
rpsblast_cdd gnl|CDD|153251 136 326 + 191 Gaps:11 98.91 184 40.11 3e-44 cd07989 LPLAT_AGPAT-like Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT PlsC) Tafazzin (product of Barth syndrome gene) and similar proteins.
rpsblast_cdd gnl|CDD|201856 149 276 + 128 Gaps:5 100.00 131 41.22 1e-28 pfam01553 Acyltransferase Acyltransferase. This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin the Barth syndrome gene.
rpsblast_cdd gnl|CDD|197792 165 278 + 114 Gaps:4 100.00 118 40.68 4e-28 smart00563 PlsC Phosphate acyltransferases. Function in phospholipid biosynthesis and have either glycerolphosphate 1-acylglycerolphosphate or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin the product of the gene mutated in patients with Barth syndrome is a member of this family.
rpsblast_cdd gnl|CDD|30553 99 324 + 226 Gaps:11 87.45 255 31.39 2e-27 COG0204 PlsC 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism].
rpsblast_cdd gnl|CDD|129621 148 275 + 128 Gaps:2 98.46 130 38.28 2e-25 TIGR00530 AGP_acyltrn 1-acyl-sn-glycerol-3-phosphate acyltransferases. This model describes the core homologous region of a collection of related proteins several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase lysophosphatidic acid acyltransferase and LPA acyltransferase.
rpsblast_cdd gnl|CDD|153253 147 324 + 178 Gaps:26 90.05 211 28.42 2e-19 cd07991 LPLAT_LPCAT1-like Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1) glycerol-3-phosphate acyltransferase 3 (GPAT3) and similar sequences.
rpsblast_cdd gnl|CDD|153254 147 326 + 180 Gaps:27 93.10 203 28.04 2e-18 cd07992 LPLAT_AAK14816-like Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase and similar proteins.
rpsblast_cdd gnl|CDD|181510 142 277 + 136 Gaps:11 11.95 1146 31.39 7e-16 PRK08633 PRK08633 2-acyl-glycerophospho-ethanolamine acyltransferase Validated.
rpsblast_cdd gnl|CDD|153244 147 293 + 147 Gaps:17 80.21 187 30.67 4e-14 cd06551 LPLAT Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis. Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT PlsB) 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT PlsC) lysophosphatidylcholine acyltransferase 1 (LPCAT-1) lysophosphatidylethanolamine acyltransferase (LPEAT also known as MBOAT2 membrane-bound O-acyltransferase domain-containing protein 2) lipid A biosynthesis lauroyl/myristoyl acyltransferase 2-acylglycerol O-acyltransferase (MGAT) dihydroxyacetone phosphate acyltransferase (DHAPAT also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).

13 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 160 315 156 G3DSA:3.40.1130.10 none none none
Phobius 195 213 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 134 152 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SMART 165 278 114 SM00563 none Phosphate acyltransferases IPR002123
Phobius 1 98 98 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
SUPERFAMILY 101 324 224 SSF69593 none none none
Phobius 214 326 113 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 123 133 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
PANTHER 94 323 230 PTHR10434 none none none
TIGRFAM 148 275 128 TIGR00530 "KEGG:00561+2.3.1.51","KEGG:00564+2.3.1.51","MetaCyc:PWY-5667","MetaCyc:PWY-5981","MetaCyc:PWY-6453","MetaCyc:PWY-7411","MetaCyc:PWY-7417","MetaCyc:PWY-7587","MetaCyc:PWY-7589","Reactome:REACT_22258","UniPathway:UPA00557" AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases IPR004552
Phobius 99 122 24 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Pfam 149 275 127 PF01553 none Acyltransferase IPR002123
Phobius 153 194 42 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none

2 Localization

Analysis Start End Length
TMHMM 194 213 19
TMHMM 102 124 22

0 Qtllist

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 52   Mitochondrion 4 0.036 0.648 NON-PLANT 52