GO:0006886
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intracellular protein transport
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The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
GO:0006810
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transport
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The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. |
GO:0005525
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GTP binding
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Interacting selectively and non-covalently with GTP, guanosine triphosphate. |
GO:0006614
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SRP-dependent cotranslational protein targeting to membrane
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The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane. |
GO:0003924
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GTPase activity
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Catalysis of the reaction: GTP + H2O = GDP + phosphate. |
GO:0005047
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signal recognition particle binding
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Interacting selectively and non-covalently with the signal recognition particle. |
GO:0005785
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signal recognition particle receptor complex
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A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex. |