Protein : Qrob_P0053270.2 Q. robur
Protein Identifier  ? Qrob_P0053270.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=20) 6.1.1.6 - Lysine--tRNA ligase. Code Enzyme  EC:6.1.1.6
Gene Prediction Quality  validated Protein length 

Sequence

Length: 130  
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0003676 nucleic acid binding Interacting selectively and non-covalently with any nucleic acid.
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0000166 nucleotide binding Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
GO:0004812 aminoacyl-tRNA ligase activity Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.
GO:0006418 tRNA aminoacylation for protein translation The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis.

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|eus:EUTSA_v10020276mg 19 128 + 110 Gaps:23 21.56 617 61.65 2e-43 hypothetical protein
blastp_kegg lcl|vvi:100242505 13 128 + 116 Gaps:23 22.42 620 58.99 4e-43 lysyl-tRNA synthetase-like
blastp_kegg lcl|pper:PRUPE_ppa016996mg 9 128 + 120 Gaps:23 24.44 585 57.34 5e-43 hypothetical protein
blastp_kegg lcl|brp:103846034 21 128 + 108 Gaps:23 21.20 618 61.83 1e-42 lysine--tRNA ligase
blastp_kegg lcl|vvi:100262532 13 128 + 116 Gaps:23 22.46 619 58.27 1e-42 lysyl-tRNA synthetase-like
blastp_kegg lcl|pmum:103323559 12 128 + 117 Gaps:23 21.21 660 57.14 4e-42 lysine--tRNA ligase-like
blastp_kegg lcl|pda:103717172 13 128 + 116 Gaps:23 22.53 617 55.40 6e-42 lysine--tRNA ligase-like
blastp_kegg lcl|pda:103700835 13 128 + 116 Gaps:23 22.53 617 55.40 7e-42 lysine--tRNA ligase-like
blastp_kegg lcl|pvu:PHAVU_003G107000g 19 128 + 110 Gaps:23 22.32 596 57.89 1e-41 hypothetical protein
blastp_kegg lcl|rcu:RCOM_0435350 21 128 + 108 Gaps:23 21.58 607 60.31 1e-41 lysyl-tRNA synthetase putative (EC:6.1.1.6)
blastp_pdb 3bju_D 32 128 + 97 Gaps:24 22.84 521 36.13 1e-17 mol:protein length:521 Lysyl-tRNA synthetase
blastp_pdb 3bju_C 32 128 + 97 Gaps:24 22.84 521 36.13 1e-17 mol:protein length:521 Lysyl-tRNA synthetase
blastp_pdb 3bju_B 32 128 + 97 Gaps:24 22.84 521 36.13 1e-17 mol:protein length:521 Lysyl-tRNA synthetase
blastp_pdb 3bju_A 32 128 + 97 Gaps:24 22.84 521 36.13 1e-17 mol:protein length:521 Lysyl-tRNA synthetase
blastp_uniprot_sprot sp|Q9ZPI1|SYK_ARATH 12 128 + 117 Gaps:23 22.36 626 55.71 3e-40 Lysine--tRNA ligase OS Arabidopsis thaliana GN At3g11710 PE 2 SV 1
blastp_uniprot_sprot sp|Q6F2U9|SYK_ORYSJ 23 128 + 106 Gaps:23 21.43 602 51.16 2e-35 Lysine--tRNA ligase OS Oryza sativa subsp. japonica GN Os03g0586800 PE 2 SV 1
blastp_uniprot_sprot sp|Q43776|SYK_SOLLC 12 128 + 117 Gaps:23 23.81 588 44.29 2e-34 Lysine--tRNA ligase OS Solanum lycopersicum GN LYSRS PE 2 SV 1
blastp_uniprot_sprot sp|Q99MN1|SYK_MOUSE 10 128 + 119 Gaps:24 23.70 595 33.33 6e-21 Lysine--tRNA ligase OS Mus musculus GN Kars PE 1 SV 1
blastp_uniprot_sprot sp|P37879|SYK_CRIGR 28 128 + 101 Gaps:24 20.60 597 36.59 4e-19 Lysine--tRNA ligase OS Cricetulus griseus GN KARS PE 1 SV 1
blastp_uniprot_sprot sp|Q9UUE6|SYKC_SCHPO 21 128 + 108 Gaps:26 22.00 591 35.38 2e-18 Lysine--tRNA ligase cytoplasmic OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN krs1 PE 3 SV 1
blastp_uniprot_sprot sp|Q15046|SYK_HUMAN 28 128 + 101 Gaps:24 20.60 597 35.77 1e-17 Lysine--tRNA ligase OS Homo sapiens GN KARS PE 1 SV 3
blastp_uniprot_sprot sp|Q22099|SYK_CAEEL 33 125 + 93 Gaps:23 19.93 572 35.09 5e-15 Lysine--tRNA ligase OS Caenorhabditis elegans GN krs-1 PE 3 SV 1
blastp_uniprot_sprot sp|P15180|SYKC_YEAST 31 128 + 98 Gaps:25 20.47 591 36.36 1e-14 Lysine--tRNA ligase cytoplasmic OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN KRS1 PE 1 SV 2
rpsblast_cdd gnl|CDD|178118 11 128 + 118 Gaps:22 25.32 553 47.14 5e-39 PLN02502 PLN02502 lysyl-tRNA synthetase.
rpsblast_cdd gnl|CDD|173607 12 128 + 117 Gaps:25 23.59 585 34.78 5e-19 PTZ00417 PTZ00417 lysine-tRNA ligase Provisional.
rpsblast_cdd gnl|CDD|188056 33 127 + 95 Gaps:25 23.39 496 25.86 4e-12 TIGR00499 lysS_bact lysyl-tRNA synthetase eukaryotic and non-spirochete bacterial. This model represents the lysyl-tRNA synthetases that are class II amino-acyl tRNA synthetases. It includes all eukaryotic and most bacterial examples of the enzyme but not archaeal or spirochete forms.
rpsblast_cdd gnl|CDD|58592 76 128 + 53 Gaps:2 47.22 108 47.06 1e-11 cd04322 LysRS_N LysRS_N: N-terminal anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop. aaRSs catalyze the specific attachment of amino acids (AAs) to their cognate tRNAs during protein biosynthesis. This 2-step reaction involves i) the activation of the AA by ATP in the presence of magnesium ions followed by ii) the transfer of the activated AA to the terminal ribose of tRNA. In the case of the class2b aaRSs the activated AA is attached to the 3'OH of the terminal ribose. Included in this group are E. coli LysS and LysU. These two isoforms of LysRS are encoded by distinct genes which are differently regulated. Eukaryotes contain 2 sets of aaRSs both of which encoded by the nuclear genome. One set concerns with cytoplasmic protein synthesis whereas the other exclusively with mitochondrial protein synthesis. Saccharomyces cerevisiae cytoplasmic and mitochondrial LysRSs have been shown to participate in the mitochondrial import of the only nuclear-encoded tRNA of S. cerevisiae (tRNAlysCUU). The gene for human LysRS encodes both the cytoplasmic and the mitochondrial isoforms of LysRS. In addition to their housekeeping role human lysRS may function as a signaling molecule that activates immune cells and tomato LysRS may participate in a root-specific process possibly connected to conditions of oxidative-stress conditions or heavy metal uptake. It is known that human tRNAlys and LysRS are specifically packaged into HIV-1 suggesting a role for LysRS in tRNA packaging..
rpsblast_cdd gnl|CDD|31383 28 128 + 101 Gaps:25 24.30 502 24.59 2e-11 COG1190 LysU Lysyl-tRNA synthetase (class II) [Translation ribosomal structure and biogenesis].
rpsblast_cdd gnl|CDD|179044 32 127 + 96 Gaps:28 23.63 491 25.86 2e-11 PRK00484 lysS lysyl-tRNA synthetase Reviewed.
rpsblast_cdd gnl|CDD|179519 41 128 + 88 Gaps:15 9.05 1094 29.29 1e-07 PRK02983 lysS lysyl-tRNA synthetase Provisional.

6 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 32 127 96 SSF50249 none none IPR012340
Gene3D 35 72 38 G3DSA:2.40.50.140 none none IPR012340
Gene3D 73 127 55 G3DSA:2.40.50.140 none none IPR012340
Pfam 75 127 53 PF01336 none OB-fold nucleic acid binding domain IPR004365
PANTHER 12 128 117 PTHR22594 "Reactome:REACT_71";signature_desc=ASPARTYL/LYSYL-TRNA SYNTHETASE none IPR018150
PANTHER 12 128 117 PTHR22594:SF4 none none none

0 Localization

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5

0 Targeting