Protein : Qrob_P0045960.2 Q. robur
Protein Identifier  ? Qrob_P0045960.2 Organism . Name  Quercus robur
Score  95.2 Score Type  egn
Protein Description  (M=1) KOG0747//KOG1371//KOG1430//KOG1502//KOG1792 - Putative NAD+-dependent epimerases [Carbohydrate transport and metabolism]. // UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase [Cell wall/membrane/envelope biogenesis]. // C-3 sterol dehydrogenase/3-beta-hydroxysteroid dehydrogenase and related dehydrogenases [Lipid transport and metabolism Amino acid transport and metabolism]. // Flavonol reductase/cinnamoyl-CoA reductase [Defense mechanisms]. // Reticulon [Intracellular trafficking secretion and vesicular transport]. Code Enzyme  EC:1.1.1.170
Gene Prediction Quality  validated Protein length 

Sequence

Length: 524  
Kegg Orthology  K07748
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+).
GO:0006694 steroid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

45 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100257631 12 509 + 498 none 88.45 563 77.31 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2-like
blastp_kegg lcl|cam:101494810 9 509 + 501 Gaps:5 88.97 562 75.60 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2-like
blastp_kegg lcl|pop:POPTR_0006s23500g 13 509 + 497 none 88.75 560 75.65 0.0 POPTRDRAFT_1081290 hypothetical protein
blastp_kegg lcl|mdm:103440612 13 518 + 506 Gaps:1 90.54 560 73.77 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2
blastp_kegg lcl|tcc:TCM_037413 13 509 + 497 none 88.75 560 76.66 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1
blastp_kegg lcl|mtr:MTR_3g105440 7 509 + 503 Gaps:5 86.70 579 74.50 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform
blastp_kegg lcl|pvu:PHAVU_009G084200g 15 495 + 481 Gaps:2 85.94 562 76.40 0.0 hypothetical protein
blastp_kegg lcl|gmx:100799363 7 509 + 503 Gaps:5 89.17 563 74.50 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2-like
blastp_kegg lcl|gmx:100816854 15 509 + 495 Gaps:2 88.43 562 74.65 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2-like
blastp_kegg lcl|fve:101292864 13 509 + 497 none 88.75 560 73.84 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2-like
blastp_pdb 1r66_A 19 375 + 357 Gaps:58 94.66 337 26.96 3e-13 mol:protein length:337 TDP-glucose-4 6-dehydratase
blastp_pdb 1r6d_A 19 375 + 357 Gaps:56 94.66 337 26.33 8e-13 mol:protein length:337 TDP-glucose-4 6-dehydratase
blastp_pdb 3ko8_A 19 293 + 275 Gaps:35 82.05 312 28.52 3e-10 mol:protein length:312 NAD-dependent epimerase/dehydratase
blastp_pdb 3icp_A 19 293 + 275 Gaps:35 82.05 312 28.52 3e-10 mol:protein length:312 NAD-dependent epimerase/dehydratase
blastp_pdb 3aw9_C 19 293 + 275 Gaps:39 81.82 308 29.37 5e-10 mol:protein length:308 UDP-galactose 4-epimerase
blastp_pdb 3aw9_B 19 293 + 275 Gaps:39 81.82 308 29.37 5e-10 mol:protein length:308 UDP-galactose 4-epimerase
blastp_pdb 3aw9_A 19 293 + 275 Gaps:39 81.82 308 29.37 5e-10 mol:protein length:308 UDP-galactose 4-epimerase
blastp_pdb 1sb9_A 19 288 + 270 Gaps:30 77.27 352 26.47 5e-09 mol:protein length:352 wbpP
blastp_pdb 1sb8_A 19 288 + 270 Gaps:30 77.27 352 26.47 5e-09 mol:protein length:352 wbpP
blastp_pdb 2p5y_A 18 364 + 347 Gaps:74 98.07 311 26.89 6e-08 mol:protein length:311 UDP-glucose 4-epimerase
blastp_uniprot_sprot sp|Q67ZE1|HSDD2_ARATH 7 505 + 499 none 88.48 564 70.74 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 OS Arabidopsis thaliana GN 3BETAHSD/D2 PE 2 SV 2
blastp_uniprot_sprot sp|Q9FX01|HSDD1_ARATH 14 456 + 443 Gaps:18 98.18 439 71.46 0.0 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 OS Arabidopsis thaliana GN 3BETAHSD/D1 PE 2 SV 1
blastp_uniprot_sprot sp|A9X4U2|HSDD3_ARATH 12 507 + 496 Gaps:10 86.99 561 43.85 1e-127 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3 OS Arabidopsis thaliana GN 3BETAHSD/D3 PE 2 SV 2
blastp_uniprot_sprot sp|Q9R1J0|NSDHL_MOUSE 9 368 + 360 Gaps:22 93.92 362 41.18 7e-77 Sterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating OS Mus musculus GN Nsdhl PE 2 SV 1
blastp_uniprot_sprot sp|Q5PPL3|NSDHL_RAT 16 368 + 353 Gaps:30 91.99 362 42.94 3e-75 Sterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating OS Rattus norvegicus GN Nsdhl PE 2 SV 1
blastp_uniprot_sprot sp|Q15738|NSDHL_HUMAN 16 368 + 353 Gaps:22 89.28 373 41.14 5e-75 Sterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating OS Homo sapiens GN NSDHL PE 1 SV 2
blastp_uniprot_sprot sp|Q3ZBE9|NSDHL_BOVIN 5 368 + 364 Gaps:22 96.63 356 39.53 5e-73 Sterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating OS Bos taurus GN NSDHL PE 2 SV 1
blastp_uniprot_sprot sp|O43050|ERG26_SCHPO 19 361 + 343 Gaps:23 95.88 340 36.20 3e-54 Sterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN erg26 PE 3 SV 1
blastp_uniprot_sprot sp|P53199|ERG26_YEAST 19 361 + 343 Gaps:24 95.99 349 35.22 3e-53 Sterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN ERG26 PE 1 SV 1
blastp_uniprot_sprot sp|A8DZE7|D42E1_DANRE 19 349 + 331 Gaps:28 83.98 387 36.31 2e-50 Short-chain dehydrogenase/reductase family 42E member 1 OS Danio rerio GN sdr42e1 PE 2 SV 1

19 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 19 294 276 PF01073 none 3-beta hydroxysteroid dehydrogenase/isomerase family IPR002225
Phobius 430 450 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 319 383 65 PTHR10366:SF242 none none none
PANTHER 14 295 282 PTHR10366:SF242 none none none
Phobius 451 470 20 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
PANTHER 14 295 282 PTHR10366 none none none
ProSiteProfiles 390 505 116 PS50845 none Reticulon domain profile. IPR003388
Phobius 403 424 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 425 429 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 1 402 402 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 490 500 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 501 520 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 333 370 38 SSF51735 none none none
SUPERFAMILY 16 301 286 SSF51735 none none none
Phobius 521 523 3 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 471 489 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Gene3D 19 362 344 G3DSA:3.40.50.720 none none IPR016040
PANTHER 319 383 65 PTHR10366 none none none
Pfam 390 517 128 PF02453 none Reticulon IPR003388

3 Localization

Analysis Start End Length
TMHMM 402 424 22
TMHMM 431 453 22
TMHMM 497 519 22

0 Qtllist

0 Targeting