Protein : Qrob_P0027790.2 Q. robur
Protein Identifier  ? Qrob_P0027790.2 Organism . Name  Quercus robur
Score  97.2 Score Type  egn
Protein Description  (M=1) K03247 - translation initiation factor eIF-3 subunit 3 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 125  
Kegg Orthology  K03247
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

3 GO Terms

Identifier Name Description
GO:0005737 cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0003743 translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
GO:0005852 eukaryotic translation initiation factor 3 complex A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.

22 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100248036 1 123 + 123 none 36.50 337 94.31 2e-77 eukaryotic translation initiation factor 3 subunit H-like
blastp_kegg lcl|sot:102601497 1 123 + 123 none 36.39 338 93.50 4e-76 eukaryotic translation initiation factor 3 subunit H-like
blastp_kegg lcl|pper:PRUPE_ppa008325mg 1 123 + 123 none 36.50 337 93.50 6e-76 hypothetical protein
blastp_kegg lcl|sot:102604600 1 123 + 123 none 36.39 338 92.68 7e-76 eukaryotic translation initiation factor 3 subunit H-like
blastp_kegg lcl|sly:101259786 1 123 + 123 none 36.39 338 92.68 7e-76 eukaryotic translation initiation factor 3 subunit H-like
blastp_kegg lcl|tcc:TCM_020132 1 123 + 123 none 36.50 337 91.87 1e-75 Eukaryotic translation initiation factor 3 subunit H isoform 2
blastp_kegg lcl|csv:101223511 1 123 + 123 none 36.50 337 91.87 2e-75 eukaryotic translation initiation factor 3 subunit H-like
blastp_kegg lcl|csv:101211860 1 123 + 123 none 36.50 337 91.87 2e-75 eukaryotic translation initiation factor 3 subunit H-like
blastp_kegg lcl|cmo:103494533 1 123 + 123 none 36.50 337 91.87 2e-75 eukaryotic translation initiation factor 3 subunit H
blastp_kegg lcl|sly:101255380 1 123 + 123 none 36.39 338 92.68 2e-75 eukaryotic translation initiation factor 3 subunit H-like
blastp_uniprot_sprot sp|Q9C5Z2|EIF3H_ARATH 1 123 + 123 none 36.50 337 82.93 2e-68 Eukaryotic translation initiation factor 3 subunit H OS Arabidopsis thaliana GN TIF3H1 PE 1 SV 2
blastp_uniprot_sprot sp|Q54UD0|EIF3H_DICDI 8 124 + 117 none 36.68 319 42.74 4e-28 Eukaryotic translation initiation factor 3 subunit H OS Dictyostelium discoideum GN eif3H PE 3 SV 1
blastp_uniprot_sprot sp|A7SA47|EIF3H_NEMVE 4 123 + 120 Gaps:1 35.84 332 39.50 3e-24 Eukaryotic translation initiation factor 3 subunit H OS Nematostella vectensis GN v1g168210 PE 3 SV 1
blastp_uniprot_sprot sp|Q5PPY6|EIF3H_XENLA 4 120 + 117 Gaps:1 34.73 334 37.93 2e-22 Eukaryotic translation initiation factor 3 subunit H OS Xenopus laevis GN eif3h PE 2 SV 1
blastp_uniprot_sprot sp|Q6P381|EIF3H_XENTR 4 120 + 117 Gaps:1 34.63 335 38.79 4e-22 Eukaryotic translation initiation factor 3 subunit H OS Xenopus tropicalis GN eif3h PE 2 SV 1
blastp_uniprot_sprot sp|A1CQB4|EIF3H_ASPCL 9 120 + 112 Gaps:22 36.71 365 35.82 9e-22 Eukaryotic translation initiation factor 3 subunit H OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) GN ACLA_025520 PE 3 SV 1
blastp_uniprot_sprot sp|Q1DHB6|EIF3H_COCIM 9 120 + 112 Gaps:22 36.71 365 33.58 2e-21 Eukaryotic translation initiation factor 3 subunit H OS Coccidioides immitis (strain RS) GN CIMG_10297 PE 3 SV 2
blastp_uniprot_sprot sp|Q5BDW0|EIF3H_EMENI 9 120 + 112 Gaps:22 36.61 366 33.58 2e-21 Eukaryotic translation initiation factor 3 subunit H OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN AN1270 PE 3 SV 2
blastp_uniprot_sprot sp|A2QQA2|EIF3H_ASPNC 9 115 + 107 Gaps:22 35.34 365 34.88 6e-21 Eukaryotic translation initiation factor 3 subunit H OS Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN An08g01790 PE 3 SV 1
blastp_uniprot_sprot sp|A1D379|EIF3H_NEOFI 9 120 + 112 Gaps:22 38.62 347 34.33 3e-20 Eukaryotic translation initiation factor 3 subunit H OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) GN NFIA_015650 PE 3 SV 1
rpsblast_cdd gnl|CDD|163696 4 124 + 121 none 45.49 266 52.89 1e-44 cd08065 MPN_eIF3h Mpr1p Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity found in eIF2h. Eukaryotic translation initiation factor 3 (eIF3) subunit h (eIF3h eIF3 subunit 3 eIF3S3 eIF3-gamma eIF3-p40) is an evolutionarily non-conserved subunit of the functional core that comprises eIF3a eIF3b eIF3c eIF3e eIF3f and eIF3h and contains the MPN domain. However it lacks the canonical JAMM motif and therefore does not show catalytic isopeptidase activity.Together with eIF3e and eIF3f eIF3h stabilizes the eIF3 complex. Results suggest that eIF3h regulates cell growth and viability and that over-expression of the gene may provide growth advantage to prostate breast and liver cancer cells. For example EIF3h gene amplification is common in late-stage prostate cancer suggesting that it may be functionally involved in the progression of the disease. It has been shown that coamplification of MYC a well characterized oncogene involved in cell growth differentiation and apoptosis and EIF3h in patients with non-small cell lung cancer (NSCLC) improves survival if treated with the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKI) Gefitinib. Plant eIF3h is implicated in translation of specific mRNAs.
rpsblast_kog gnl|CDD|36773 4 123 + 120 Gaps:2 35.99 339 34.43 7e-20 KOG1560 KOG1560 KOG1560 Translation initiation factor 3 subunit h (eIF-3h) [Translation ribosomal structure and biogenesis].

2 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 4 124 121 PTHR10410 none none none
PANTHER 4 124 121 PTHR10410:SF3 none none IPR027524

0 Localization

8 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran_2000_2002_QTL7_Delta.F Qrob_Chr09 9 v_5944_442 s_1BA1PC_866 23.51 10,96 35,74 lod 4.1466 0.041
Bourran2_2003_QTL11_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 4,16 48,16 lod 2,3 5,1
Bourran2_2004_QTL12_peak_Bud_burst_3P Qrob_Chr09 9 s_1BDO6G_250 s_1A83AM_496 34,31 9,31 44,31 lod 3,6 7,6
Bourran2_2004_QTL14_peak_Bud_burst_A4 Qrob_Chr09 9 s_1BY6BQ_440 s_1AOIKO_756 16,83 10,33 22,33 lod 3,8 9
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nSecLBD_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 35,81 34,88 37,45 lod 4.4 10.4
PM_1999_QTL15_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 9,16 47,16 lod 3,6 6,5
Bourran1_2003_QTL5_peak_Bud_burst_3P Qrob_Chr09 9 s_1ATM17_504 s_1AYZFM_899 29,81 19,81 41,81 lod 3,3 8,9

0 Targeting